Unique ID issued by UMIN | UMIN000000708 |
---|---|
Receipt number | R000000844 |
Scientific Title | Efficacy and Safety of mizoribine for MPO-ANCA associated vasculitis; A multicenter randomized controlled trial (Mizoribin for ANCA RPGN Relapse-Prevention study:MARPGN study) |
Date of disclosure of the study information | 2007/05/06 |
Last modified on | 2013/05/07 08:13:07 |
Efficacy and Safety of mizoribine for MPO-ANCA associated vasculitis; A multicenter randomized controlled trial (Mizoribin for ANCA RPGN Relapse-Prevention study:MARPGN study)
MARPGN study
Efficacy and Safety of mizoribine for MPO-ANCA associated vasculitis; A multicenter randomized controlled trial (Mizoribin for ANCA RPGN Relapse-Prevention study:MARPGN study)
MARPGN study
Japan |
MPO-ANCA associated vasculitis
Medicine in general | Nephrology | Clinical immunology |
Others
NO
To assess efficacy and safety of mizoribine monitoring the serum concentration for MPO-ANCA associated vasculitis
Safety,Efficacy
Confirmatory
Explanatory
Not applicable
BVAS score, time from remmision to relapse, relapse rate
MPO-ANCA titer, CRP, GFR, amount dose of corticosteroid through the study
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
No treatment
YES
YES
Institution is considered as adjustment factor in dynamic allocation.
NO
Central registration
2
Treatment
Medicine |
treatment with mizoribine according to the GFR once a day
no treatment with mizoribine
20 | years-old | <= |
80 | years-old | > |
Male and Female
Patients in remmision state of
ANCA-associated vasculitis
Patients with allergy with Mizoribine
Patients with leucocytosis(<3000/mm3)
Patients treated with other immunosuppression drug within four weeks
126
1st name | |
Middle name | |
Last name | Kunihiro Yamagata |
Division of Clinical Sciences, Faculty of Medicine, University of Tsukuba
Department of Nephrology
1-1-1,Ten-nodai,Tsukuba,Ibaraki
029-853-3202
1st name | |
Middle name | |
Last name | Kunihiro Yamagata |
Division of Clinical Sciences, Faculty of Medicine, University of Tsukuba
Department of Nephrology
1-1-1,Ten-nodai,Tsukuba,Ibaraki
029-853-3202
kidney@md.tsukuba.ac.jp
Department of Nephrology, Division of Clinical Sciences, Faculty of Medicine, University of Tsukuba
Ministry of Health, Labour and Welfare
Japan
none
Asahi Kasei Pharma Corporation
NO
2007 | Year | 05 | Month | 06 | Day |
Unpublished
Completed
2007 | Year | 03 | Month | 16 | Day |
2007 | Year | 03 | Month | 01 | Day |
2012 | Year | 12 | Month | 31 | Day |
2007 | Year | 05 | Month | 06 | Day |
2013 | Year | 05 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000000844
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |