Unique ID issued by UMIN | UMIN000000713 |
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Receipt number | R000000848 |
Scientific Title | Efficacy of PEG-IFN alfa-2b plus Ribabirin and HMG-CoA reductase inhibitor combination antiviral therapy ; pilot study |
Date of disclosure of the study information | 2007/05/09 |
Last modified on | 2009/11/15 21:00:17 |
Efficacy of PEG-IFN alfa-2b plus Ribabirin and HMG-CoA reductase inhibitor combination antiviral therapy ; pilot study
Efficacy of PEG-IFN alfa-2b plus Ribabirin and HMG-CoA reductase inhibitor combination therapy
Efficacy of PEG-IFN alfa-2b plus Ribabirin and HMG-CoA reductase inhibitor combination antiviral therapy ; pilot study
Efficacy of PEG-IFN alfa-2b plus Ribabirin and HMG-CoA reductase inhibitor combination therapy
Japan |
Chronic hepatitis C
Hepato-biliary-pancreatic medicine |
Others
NO
To confirm the efficacy and safety of peginterferon alfa-2b plus ribavirin and HMG-CoA reductase inhibitor combination therapy of patients with HCV.
Safety,Efficacy
virologic response
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
HMG-CoA reductase inhibitor
20 | years-old | <= |
Not applicable |
Male and Female
genotype 1 and high pretreatment viremia and high pretretment viremia at 24weeks inspite of PEG-IFN alfa-2b plus Ribabirin therapy
1) Patients receiving shosaiko-to 2) Autoimmune hepatitis 3) History of hypersensitivity to PEG-IFN alpha-2b or other interferons 4) History of hypersensitivity to biological products such as vaccine 5) Decompenstated liver cirrhosis 6) HCC, malignat tumor 7) With or with a history of severe psychosis such as severe depression, suicidal ideation or attempt, etc. 8) Pregnant or lactating women and women who may be pregnant 9) Judged by investigator not to be appropriate for inclusion in this study
10
1st name | |
Middle name | |
Last name | Kazuaki Chayama |
graduate school of biomedical science, Hiroshima university.
Department and medicine and molecular science
1-2-3 kasumi, minami-ku, Hiroshima 734-8551
1st name | |
Middle name | |
Last name | Tomokazu Kawaoka |
graduate school of biomedical science, Hiroshima university
Department and medicine and molecular science
1-2-3 kasumi, minami-ku, Hiroshima
Hiroshima liver study group
none
Self funding
NO
2007 | Year | 05 | Month | 09 | Day |
Unpublished
Terminated
2006 | Year | 12 | Month | 05 | Day |
2006 | Year | 12 | Month | 01 | Day |
2007 | Year | 10 | Month | 01 | Day |
2007 | Year | 05 | Month | 09 | Day |
2009 | Year | 11 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000000848
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