Unique ID issued by UMIN | UMIN000000909 |
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Receipt number | R000001096 |
Scientific Title | Effects of traditional Chinese medicine for chorea in the Huntington's disease. |
Date of disclosure of the study information | 2008/05/16 |
Last modified on | 2010/09/22 02:29:30 |
Effects of traditional Chinese medicine for chorea in the Huntington's disease.
Traditional Chinese medicine for Huntington's disease
Effects of traditional Chinese medicine for chorea in the Huntington's disease.
Traditional Chinese medicine for Huntington's disease
Japan |
Huntington's disease
Neurology |
Others
YES
To evaluate the effect of traditional Chinese medicines for the chorea in Huntington's disease
Safety,Efficacy
Exploratory
Pragmatic
Phase I,II
Unified Huntington's Disease Rating Scale (UHDRS)
Cognitive function, ADL, Use of rescue drug, toralance
Interventional
Cross-over
Non-randomized
Open -but assessor(s) are blinded
Active
2
Treatment
Medicine |
Step1 To take Chai hu jia long gu mu li tang 56 days
Step2 Wash out 28 days
Step3 To take Yigan San 56 days
Step1 To take Yigan San 56 days
Step2 Wash out 28 days
Step3 To take Chai hu jia long gu mu li tang 56 days
40 | years-old | <= |
80 | years-old | > |
Male and Female
1.Clinically diagnosed as Huntington's disease according to ICD10 with abnormal prolongation of CAG repeat in IT15 gene.
2.At least one subscore of UHDRS is more than 3.
3.Serum potassium level is within the normal limit.
4.Stayed in the hospital over 5 years
5.A single care giver takes care each patient.
1.with any malignancy
2.with severe heart disease, liver disease, blood disease, respiratory disease and any other severe diseases influenced on the patients states
3.With any neurodegenerating diseases other than Huntington's disease
4.Alcohol abuse, drug abuse, metabolic toxicity, chronic inflammatory diseases
5.Who can not take herbal medicine per os.
6.Who are perscribed any antipsychotics newly in the observation period.
7. Others who are judged as inadequate by attending doctors.
4
1st name | |
Middle name | |
Last name | Koh Iwasaki |
Graduate School of Medicine, Tohoku University
Center for Asian Traditional Medicine
1-1 Seiryo-cho, Aoba Ward, Sendai City Miyagi Japan
022-717-7182
1st name | |
Middle name | |
Last name | Koh Iwasaki |
Graduate School of Medicine, Tohoku University
Center for Asian Traditional Medicine
1-1 Seiryo-cho, Aoba Ward, Sendai City Miyagi Japan
022-717-7182
QFG03604@nifty.com
Yonezawa National Hospital
Yonezawa National Hospital.
Japan
NO
2008 | Year | 05 | Month | 16 | Day |
Published
Mov Disord. 2009 Feb 15;24(3):453-5.
Completed
2007 | Year | 09 | Month | 30 | Day |
2007 | Year | 10 | Month | 01 | Day |
2008 | Year | 03 | Month | 01 | Day |
2008 | Year | 04 | Month | 01 | Day |
2008 | Year | 04 | Month | 01 | Day |
2008 | Year | 05 | Month | 01 | Day |
2007 | Year | 11 | Month | 27 | Day |
2010 | Year | 09 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001096
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