Unique ID issued by UMIN | UMIN000000925 |
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Receipt number | R000001113 |
Scientific Title | A prospective study on the effects of gene polymorphisms on postoperative pain management in patients undergoing orthognathic surgery |
Date of disclosure of the study information | 2007/12/03 |
Last modified on | 2015/06/03 13:01:11 |
A prospective study on the effects of gene polymorphisms on postoperative pain management in patients undergoing orthognathic surgery
A study on gene polymorphism effects on postoperative pain management
A prospective study on the effects of gene polymorphisms on postoperative pain management in patients undergoing orthognathic surgery
A study on gene polymorphism effects on postoperative pain management
Japan |
Pain
Anesthesiology |
Others
YES
To develop a way of personalized pain treatment by examining associations between gene polymorphisms and postoperative opioid requirements or intensity of postoperative pain in patients undergoing orthognathic surgery
Others
Sensitivity to analgesics
Exploratory
Associations between gene polymorphisms and postoperative opioid requirements or intensity of postoperative pain during 24 hours after surgery
Observational
15 | years-old | <= |
60 | years-old | >= |
Male and Female
Patients who undergo orthognathic surgery and agree to participate in the study with written informed consent
Patients less than 15 years and more than 60 years or those with severe complications
300
1st name | |
Middle name | |
Last name | Kazutaka Ikeda |
Tokyo Metropolitan Institute of Medical Science
Addictive Substance Project
2-1-6 Kamikitazawa, Setagaya-ku, Tokyo
03-6834-2379(EXT-3825)
ikeda-kz@igakuken.or.jp
1st name | |
Middle name | |
Last name | Kazutaka Ikeda |
Tokyo Metropolitan Institute of Medical Science
Addictive Substance Project
2-1-6 Kamikitazawa, Setagaya-ku, Tokyo
03-6834-2379(EXT-3825)
ikeda-kz@igakuken.or.jp
Tokyo Metropolitan Institute of Medical Science
Ministry of Health, Labour and Welfare
Japan
Tokyo Dental College Suidobashi Hospital
NO
2007 | Year | 12 | Month | 03 | Day |
Partially published
http://www.igakuken.or.jp/abuse/publications.html
American Society of Human Genetics (ASHG) 59th Annual Meeting
12th International Congress of Human Genetics (ICHG) / American Society of Human Genetics (ASHG) 61st Annual Meeting
Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 21th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 41th Annual Meeting
Japanese Society of Clinical Neuropsychopharmacology (JSCNP) 22th Annual Meeting / Japanese Society of Neuropsychopharmacology (JSNP) 42th Annual Meeting
Purine 2012
European Human Genetics Conference 2013
XXIst World Congress of Psychiatric Genetics
Method of evaluating drug-sensitivity by analyzing the voltage-dependent Ca2+ channel gene
Method of evaluating drug-sensitivity by analyzing the adrenergic receptor genes
Method of evaluating drug-sensitivity and vulnerability to diseases by analyzing the cyclic-AMP response element-binding protein gene
Method of evaluating drug-sensitivity by analyzing several genes related to analgesia
Fukuda K, Hayashida M, Ide S, Saita N, Kokita Y, Kasai S, Nishizawa D, Ogai Y, Hasegawa J, Nagashima M, Tagami M, Komatsu H, Sora I, Koga H, Kaneko Y, Ikeda K.
Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery.
Pain. 2009 Dec 15;147(1-3):194-201. doi: 10.1016/j.pain.2009.09.004. Epub 2009 Sep 26.
Nishizawa D, Fukuda K, Kasai S, Hasegawa J, Aoki Y, Nishi A, Saita N, Koukita Y, Nagashima M, Katoh R, Satoh Y, Tagami M, Higuchi S, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Koga M, Arinami T, Kaneko Y, Hayashida M, Ikeda K.
Genome-wide association study identifies a potent locus associated with human opioid sensitivity.
Mol Psychiatry. 2014 Jan;19(1):55-62. doi: 10.1038/mp.2012.164. Epub 2012 Nov 27.
Open public recruiting
2004 | Year | 03 | Month | 23 | Day |
2005 | Year | 05 | Month | 01 | Day |
2016 | Year | 05 | Month | 01 | Day |
A study examining associations between gene polymorphisms and postoperative opioid requirements or intensity of postoperative pain using patient samples
2007 | Year | 12 | Month | 03 | Day |
2015 | Year | 06 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001113
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