Unique ID issued by UMIN | UMIN000005240 |
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Receipt number | R000001124 |
Scientific Title | Optimal dose of Cropidogrel to prevent stent thrombosis after drug-eluting stent implantation in Japanese : a randomised control trial |
Date of disclosure of the study information | 2011/03/11 |
Last modified on | 2015/05/05 11:53:56 |
Optimal dose of Cropidogrel to prevent stent thrombosis after drug-eluting stent implantation in Japanese : a randomised control trial
Optimal dose of Cropidogrel to prevent stent thrombosis after drug-eluting stent implantation in Japanese : a randomised control trial
Optimal dose of Cropidogrel to prevent stent thrombosis after drug-eluting stent implantation in Japanese : a randomised control trial
Optimal dose of Cropidogrel to prevent stent thrombosis after drug-eluting stent implantation in Japanese : a randomised control trial
Japan |
coronary artery disease
Cardiology |
Others
NO
Optimal dose of Cropidogrel to prevent stent thrombosis after drug-eluting stent impantation in Japanese
Safety,Efficacy
MACE (major adverse cardiac event), side effect of clopidogrel, bleedin event
Interventional
Parallel
Randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
100 patients who underwent coronary intervention and deployed drug-eluting stent at Chiba university hospital since November 2007 are randomly assigned to clopidogrel 75mg/day group. After at least 12 months period, we evaluate stent thrombosis, side effect of clopidogrel and bleeding event.
100 patients who underwent coronary intervention and deployed drug-eluting stent at Chiba university hospital since November 2007 are randomly assigned to clopidogrel 50mg/day group. After at least 12 months period, we evaluate stent thrombosis, side effect of clopidogrel and bleeding event.
20 | years-old | <= |
80 | years-old | >= |
Male and Female
Patients who underwent drug-eluting stent implantation and not meet the exclusion criteria
1 Acute Myocardial Infarction and coronary disease associate with thrombosis
2 complicated active bleeding , diathesis of thrombosis
3 neutropenia
4 thrombocytepenia
5 sever liver dysfunction
6 chronic renal failure
7 sever uncontroled hypertension
8 allergy for clopidgrel and/or aspirin
9 shock stete sta
10 chronic cardiad failure
11 body weight<40 kg
12 pregnancy
13 comorbid malignancy tumor
14 age > 80
15 poor expectation for prognosis by any cause
200
1st name | |
Middle name | |
Last name | Kenji Ohkubo |
Department of Cardiovascular Science and Medicine Chiba University Graduate School of Medicine
Department of Cardiovascular Science and Medicine
1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8677, Japan
043-222-7171
kenji_ookubo@yahoo.co.jp
1st name | |
Middle name | |
Last name | Kenji Ohkubo |
Department of Cardiovascular Science and Medicine Chiba University Graduate School of Medicine
Department of Cardiovascular Science and Medicine
1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8677, Japan
043-222-7171
kenji_ookubo@yahoo.co.jp
Department of Cardiovascular Science and Medicine Chiba University Graduate School of Medicine
Department of Cardiovascular Science and Medicine Chiba University Graduate School of Medicine
Other
NO
2011 | Year | 03 | Month | 11 | Day |
Published
Completed
2007 | Year | 10 | Month | 31 | Day |
2007 | Year | 11 | Month | 01 | Day |
2011 | Year | 03 | Month | 11 | Day |
2015 | Year | 05 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001124
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