Unique ID issued by UMIN | UMIN000001254 |
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Receipt number | R000001528 |
Scientific Title | To compare therapeutic effect of Glycyrrhizic Acid and H1-receptor antagonist for acute urticaria : a multicenter, prospective, single-blind, randomized controlled trial |
Date of disclosure of the study information | 2008/07/17 |
Last modified on | 2012/07/19 09:49:01 |
To compare therapeutic effect of Glycyrrhizic Acid and H1-receptor antagonist for acute urticaria
: a multicenter, prospective, single-blind, randomized controlled trial
To compare therapeutic effect of Glycyrrhizic Acid and H1-receptor antagonist for acute urticaria
: a multicenter, prospective, single-blind, randomized controlled trial
To compare therapeutic effect of Glycyrrhizic Acid and H1-receptor antagonist for acute urticaria
: a multicenter, prospective, single-blind, randomized controlled trial
To compare therapeutic effect of Glycyrrhizic Acid and H1-receptor antagonist for acute urticaria
: a multicenter, prospective, single-blind, randomized controlled trial
Japan |
acute urticaria
Medicine in general | Clinical immunology | Dermatology |
Others
NO
For the treatment of acute urticaria, use of H1-receptor antagonist is popular in Japan, although glycyrrhizic acid has been sometimes used in Japan. We aimed to assess the efficacy and safety of intravenous H1-receptor antagonist with Glycyrrhizic Acid injestion for the treatment of acute urticaria.
Safety,Efficacy
A visual analog scale (VAS) for pruritus as a patient's subjective measurement
Evaluation of the itch based on a new rating scale (a 'itch score'), a final global improvement rating
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Active
NO
NO
Institution is not considered as adjustment factor.
NO
Numbered container method
2
Treatment
Medicine |
Intravenous H1-receptor antagonist (Chlorpheniramine Maleate)
Glycyrrhizic Acid injestion
20 | years-old | <= |
80 | years-old | > |
Male and Female
Patients who are newly diagnosed as an acute moderate or severe urticaria (defined by Japanese guideline); who has had no acute urticaria in 1 month before entry; and no condition requiring emergency management.
Patients who are unreliable in following physicians' directives; did not use of any other H1-receptor antagonists, steroids, or antiallergy agent within 48 hours before entry; have no history of contraindication of H1-receptor antagonist, Glycyrrhizic Acid injestion, or similar articles; are pregnant or in lactation period; have to drive back home by oneself; and are in other conditions at the discretion of the individual physician
60
1st name | |
Middle name | |
Last name | Hiromi Watanabe |
Yuzawa Community Medical Center
Community and family medicine
2877-1, Yuzawa, Yuzawa-machi, Minami-uonuma, Niigata, 949-6101
025-780-6543
1st name | |
Middle name | |
Last name | Hiromi Watanabe |
Yuzawa Community Medical Center
Community and family medicine
2877-1, Yuzawa, Yuzawa-machi, Minami-uonuma, Niigata, 949-6101
025-780-6543
Yuzawa Community Medical Center
The Japanese Academy of Family Medicine
Non profit foundation
Tsukuba Medical Center Hospital
NO
湯沢町保健医療センター(新潟県)、筑波メディカルセンター病院(茨城県)、水戸協同病院(茨城県)
2008 | Year | 07 | Month | 17 | Day |
Unpublished
Completed
2007 | Year | 06 | Month | 30 | Day |
2007 | Year | 07 | Month | 01 | Day |
2008 | Year | 10 | Month | 01 | Day |
2008 | Year | 07 | Month | 17 | Day |
2012 | Year | 07 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001528
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