Unique ID issued by UMIN | UMIN000001268 |
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Receipt number | R000001543 |
Scientific Title | oral desensitization therapy in children with food allergy |
Date of disclosure of the study information | 2008/12/15 |
Last modified on | 2017/01/30 10:46:23 |
oral desensitization therapy in children with food allergy
oral desensitization therapy in children with food allergy
oral desensitization therapy in children with food allergy
oral desensitization therapy in children with food allergy
Japan |
food allergy
Pediatrics |
Others
NO
The aim of this study is to evaluate the efficacy and safety of oral desensitization therapy in children with food allergy.
Safety,Efficacy
difference of tolerance rate between treatment group and elimination group
Interventional
Parallel
Randomized
Open -no one is blinded
No treatment
2
Treatment
Food |
gradually increased ingestion of egg or milk
elimination of egg or milk
3 | years-old | <= |
15 | years-old | > |
Male and Female
patients with immediate allergic reaction for egg or milk in double blind placebo control food challenge test
patients with poorly controlled asthma or atopic dermatitis
72
1st name | |
Middle name | |
Last name | Yukihiro Ohya |
National Center for Child Health and Development
Division of Allergy
2-10-1 Okura Setagaya-ku Tokyo
1st name | |
Middle name | |
Last name |
National Center for Child Health and Development
Division of Allergy
National Center for Child Health and Development Division of Allergy
TAIHO PHARMACEUTICAL CO, LTD
Profit organization
NO
2008 | Year | 12 | Month | 15 | Day |
Published
https://www.ncbi.nlm.nih.gov/pubmed/27914210
Eight of the 14 (57%) patients in the OIT group passed 4 g of dry egg powder whereas none of the 16 patients in the EE group did. All 14 patients in the OIT group showed increased threshold for egg powder in the second OFC compared to the baseline. There was no significant change in egg white-specific IgE levels during therapy. After therapy, egg white-specific IgG4 levels increased significantly in the OIT group, but not in the EE group.
Completed
2005 | Year | 11 | Month | 01 | Day |
2005 | Year | 11 | Month | 01 | Day |
2009 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2008 | Year | 07 | Month | 25 | Day |
2017 | Year | 01 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001543
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