Unique ID issued by UMIN | UMIN000001598 |
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Receipt number | R000001920 |
Scientific Title | Effect of ghrelin on airway inflammation in patients with chronic lower respiratory infection |
Date of disclosure of the study information | 2009/01/05 |
Last modified on | 2012/05/02 15:59:37 |
Effect of ghrelin on airway inflammation in patients with chronic lower respiratory infection
Effect of ghrelin on airway inflammation
Effect of ghrelin on airway inflammation in patients with chronic lower respiratory infection
Effect of ghrelin on airway inflammation
Japan |
chronic lower respiratory infection
Pneumology |
Others
NO
To clarify whether ghrelin suppresses airway inflammation
Efficacy
volume of sputum
Interventional
Cross-over
Randomized
Double blind -all involved are blinded
Placebo
2
Treatment
Medicine |
Human ghrelin (2microgram/kg, 20 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. After one week interval, the same volume of salin was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously.
Twenty ml of salin was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. After one week interval, human ghrelin (2microgram/kg, 20 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously.
Not applicable |
80 | years-old | >= |
Male and Female
1) persistent productive cough with purulent sputum for >6 months
2) isolation of multidrug-resistant pathogens from sputum
3) BMI<21kg/m2
1) patients with diabetes mellitus, severe cardiac disease, hepatic disease, renal insufficiency
2) pregnant women
3) patients with infections in other organs than the lungs
40
1st name | |
Middle name | |
Last name | Nakazato Masamitsu |
Miyazaki University School of Medicine
Third Department of Internal Medicine
Kihara 5200, kiyotake, Miyazaki
1st name | |
Middle name | |
Last name |
Miyazaki University School of Medicine
Third Department of Internal Medicine
Miyazaki University School of Medicine
Ministry of Health, Labour and Welfare
NO
2009 | Year | 01 | Month | 05 | Day |
Unpublished
2008 | Year | 12 | Month | 01 | Day |
2009 | Year | 01 | Month | 01 | Day |
2011 | Year | 03 | Month | 01 | Day |
2008 | Year | 12 | Month | 25 | Day |
2012 | Year | 05 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001920
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