Unique ID issued by UMIN | UMIN000001915 |
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Receipt number | R000002309 |
Scientific Title | preventive effects of isosorbide dinitrate / nicorandil on myocardial ischemia during postoperative period in patients with coronary risk underwent non-cardiac surgeries |
Date of disclosure of the study information | 2009/05/21 |
Last modified on | 2014/05/30 15:42:24 |
preventive effects of isosorbide dinitrate / nicorandil on myocardial ischemia during postoperative period in patients with coronary risk underwent non-cardiac surgeries
preventive effects of isosorbide dinitrate / nicorandil on myocardial ischemia during postoperative period in patients underwent non-cardiac surgeries
preventive effects of isosorbide dinitrate / nicorandil on myocardial ischemia during postoperative period in patients with coronary risk underwent non-cardiac surgeries
preventive effects of isosorbide dinitrate / nicorandil on myocardial ischemia during postoperative period in patients underwent non-cardiac surgeries
Japan |
Postoperrative ischemic heart disease(postoperative)
Intensive care medicine |
Others
NO
The risk of myocardial ischemia, arrhythmia during perioperative period increases in the patients with coronary risks such as hypertention, lipid metabolic disorder. Our purpose is to investigate the preventive effect of isosorbide dinitrate / nicorandil on myocardial ischemia during postoperative period in patients with coronary risk who are going under non-cardiac surgeries.
Safety,Efficacy
Confirmatory
Pragmatic
Not applicable
myocardial ischemia(ECG),
arrhythmia, symptoms of heart failure, chest pain, heart attack
adverse effect
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
No treatment
3
Prevention
Medicine |
non-treatment with vasodilators,
anti-anginal agents during staying
in intensive care unit
ISDN (0.5micro-g/kg/min)
nicorandil(0.6micro-g/kg/min)
40 | years-old | <= |
Not applicable |
Male and Female
patients undergoing non-cardiac surgeries who are evaluated into classes of ASA 1/2 and have over 10 points of coronary risk index
contraindication to medicines
treatment with beta blockers before surgery
300
1st name | |
Middle name | |
Last name | Takuyo Misumi |
Kobe University Hospital
Department of Intensive Care Unit
7-5-2,Kusunoki-cho,chuo-ku,kobe,Hyogo, 650-0017,Japan
078-382-5111
misumi@med.kobe-u.ac.jp
1st name | |
Middle name | |
Last name | Misumi Takuyo |
Kobe University Hospital
Department of Intensive Care Unit
7-5-2,Kusunoki-cho,chuo-ku,kobe,Hyogo, 650-0017,Japan
078-382-5111
misumi@med.kobe-u.ac.jp
Kobe University Graduate School of Medicine,
Division of Anesthesiology and Perioperative Medicine
Kobe University Graduate School of Medicine,
Division of Anesthesiology and Perioperative Medicine
Other
NO
2009 | Year | 05 | Month | 21 | Day |
Unpublished
Terminated
2009 | Year | 04 | Month | 22 | Day |
2009 | Year | 06 | Month | 01 | Day |
2014 | Year | 06 | Month | 01 | Day |
2009 | Year | 04 | Month | 28 | Day |
2014 | Year | 05 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002309
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