Unique ID issued by UMIN | UMIN000002019 |
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Receipt number | R000002463 |
Scientific Title | The significance of new lightning systems, Narrow band imaging and Autofluorescence imaging, in the diagnosis of gastrointestinal tumors |
Date of disclosure of the study information | 2009/07/13 |
Last modified on | 2018/09/13 16:12:12 |
The significance of new lightning systems, Narrow band imaging and Autofluorescence imaging, in the diagnosis of gastrointestinal tumors
The significant of NBI and AFI in diagnosing gastrointestinal tumors
The significance of new lightning systems, Narrow band imaging and Autofluorescence imaging, in the diagnosis of gastrointestinal tumors
The significant of NBI and AFI in diagnosing gastrointestinal tumors
Japan |
Gastrointestinal tumors
Gastroenterology | Hepato-biliary-pancreatic medicine | Hematology and clinical oncology |
Gastrointestinal surgery | Hepato-biliary-pancreatic surgery | Laboratory medicine |
Operative medicine |
Malignancy
YES
To elucidate the efficacy of Narrow band imaging and Autofluorescence imaging in diagnosing gastrointestinal tumors
Efficacy
Confirmatory
Explanatory
Not applicable
1) The relationship between AFI and histological or genetic features of gastrointestinal tumors
2) The relationship between NBI and histological or genetic features of gastrointestinal tumors
1) Interobserver consistency in the assessment of AFI
2) Interobserver consistency in the assessment of NBI
3) Histological factors affecting AFI and NBI
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
No treatment
2
Diagnosis
Gene | Device,equipment |
Endoscopy with special lightning systems.
1)Instruments: CV-260S, CLV-260SL, CF-FH260AZI (Olympus Corp. Japan)
2)Features: An AFI and NBI image are easily obtained at any time by manipulating a button on the control portion. The strength of fluorescence emitted from intestinal tissues of AFI images are quantified with image-analytical software. This quantification is performed by an endoscopist who do not participate in assessing the visual classification and is aware of no endoscopic or histological information.
3)Endoscopic procedure
AFI images obtained from the lesions are evaluated as predominant color intensities depending on the autofluorescence reflection. NBI images obtained from the lesions are evaluated as the density and irregularity of tumor vessels. AFI and NBI images are visually evaluated by three endoscopists during the procedure without any histological information. The dysplastic grade is diagnosed by a pathologist with no clinical and endoscopic information according to the Vienna classification. In addition, the quatification od AFI images is calculated right after the endoscopic examination by endoscopists who do not participate in assessing the visual classification and have no knowledge of the endoscopic and histological information.
Conventional endoscopy.
1)Instruments: CV-260S, CLV-260SL, CF-FH260AZI (Olympus Corp. Japan)
2)Features: An AFI and NBI image are easily obtained at any time by manipulating a button on the control portion. The strength of fluorescence emitted from intestinal tissues of AFI images are quantified with image-analytical software. This quantification is performed by an endoscopist who do not participate in assessing the visual classification and is aware of no endoscopic or histological information.
3)Endoscopic procedure
AFI images obtained from the lesions are evaluated as predominant color intensities depending on the autofluorescence reflection. NBI images obtained from the lesions are evaluated as the density and irregularity of tumor vessels. AFI and NBI images are visually evaluated by three endoscopists during the procedure without any histological information. The dysplastic grade is diagnosed by a pathologist with no clinical and endoscopic information according to the Vienna classification. In addition, the quatification od AFI images is calculated right after the endoscopic examination by endoscopists who do not participate in assessing the visual classification and have no knowledge of the endoscopic and histological information.
12 | years-old | <= |
Not applicable |
Male and Female
Patients who need to undergo endoscopy by any reasons
Patients with severe cardiac disease
Patients with severe renal dysfunction
Patients with severe liver dysfunction
Patients with severe infectious disease
Patients with severe dehydration or malnutrition
Patients with abnormal blood coagulation
Patients with severe dilatation or perforation in the stomach or intestine
600
1st name | |
Middle name | |
Last name | Mikihiro Fujiya |
Asahikawa Medical University
Division of Gastroenterology and Hematology/Oncology, Department of Medicine
2-1-1-1, Midorigaoka-Higashi, Asahikawa, Hokkaido, 078-8510, Japan
81-166-68-2462
fjym@asahikawa-med.ac.jp
1st name | |
Middle name | |
Last name | Mikihiro Fujiya |
Asahikawa Medical University
Division of Gastroenterology and Hematology/Oncology, Department of Medicine
2-1-1-1, Midorigaoka-higashi, Asahikawa, Hokkaido, Japan
81-166-68-2462
fjym@asahikawa-med.ac.jp
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University
none
Other
NO
旭川医科大学病院(北海道)
Asahikaw Medical University Hospital (Hokkaido)
2009 | Year | 07 | Month | 13 | Day |
Unpublished
Completed
2007 | Year | 04 | Month | 01 | Day |
2007 | Year | 04 | Month | 01 | Day |
2017 | Year | 03 | Month | 01 | Day |
2009 | Year | 05 | Month | 30 | Day |
2018 | Year | 09 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002463
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