Unique ID issued by UMIN | UMIN000002455 |
---|---|
Receipt number | R000002659 |
Scientific Title | Study of Arthralgia and Vasomotor Symptoms in Japanese Postmenopausal Women Treated with Anastrozole |
Date of disclosure of the study information | 2009/09/06 |
Last modified on | 2020/03/15 12:42:20 |
Study of Arthralgia and Vasomotor Symptoms in Japanese Postmenopausal Women Treated with Anastrozole
SAVS-JP
Study of Arthralgia and Vasomotor Symptoms in Japanese Postmenopausal Women Treated with Anastrozole
SAVS-JP
Japan |
Postmenopausal breast cancers
Breast surgery |
Malignancy
YES
Evalation of arthralgia symptoms among postmenopasual Japanese breast cancer patients treated with anastrozole.
Others
Analysis of symptoms accompanied with the drug.
Frequency of arthralgian and vasomotor symptoms.
Observational
Not applicable |
Not applicable |
Female
Postmenopausal breast cancer patients.
Bilateral breast cancer
Double cancer within 5 years after treatment
500
1st name | Yasuo |
Middle name | |
Last name | Miyoshi |
Hyogo College of Medicine
Department of Surgery, Division of Breast and Endocrine Surgery
663-8501
1-1 Mukogawacho, Nishinomiya city, Hyogo
0798456374
ymiyoshi@hyo-med.ac.jp
1st name | Yasuo |
Middle name | |
Last name | Miyoshi |
Hyogo College of Medicine
Department of Surgery, Division of Breast and Endocrine Surgery
663-8501
1-1 Mukogawa Nishinomiya
0798456374
ymiyoshi@hyo-med.ac.jp
Department of Surgery, Hyogo College of Medicine
Funding of Hyogo College of Medicine
Other
Institutional Review Board of Hyogo College of Medicine
Mukogawa 1-1, Nishinomiya City
0798456374
rinri@hyo-med.ac.jp
NO
兵庫医科大学、兵庫県立がんセンター、関西ろうさい病院、さきたクリニック、神鋼病院、甲南病院、兵庫県立西宮病院、茶屋町ブレストクリニック
、西神戸医療センター、明和病院、尼崎厚生会立花病院、神戸百年記念病院、川西市立川西病院、岡本クリニック、伊丹市立伊丹病院、兵庫県立加古川病院、隈病院、六甲アイランド病院、近畿中央病院、県立塚口病院、大山病院、橋本クリニック、みやうちクリニック、にしかわクリニック、新日鐡広畑病院、神戸市立医療センター中央市民病院、協同病院、宝塚市立病院、神戸大学 乳腺・内分泌外科、こくふブレストクリニック、西田クリニック
2009 | Year | 09 | Month | 06 | Day |
Unpublished
Partially published
https://www.ncbi.nlm.nih.gov/pubmed/26411314
391
PROs from 362 patients (92.6 %) were obtained. New or worsening from baseline of joint symptoms were reported by 260 patients (71.8 %). More than 90 % of the symptoms were mild or moderate. Multivariate analysis showed that a short time span after menopause [odds ratio (OR) 0.95, 95 % confidence interval (CI) 0.90-0.99; P = 0.02] and adjuvant chemotherapy (OR 2.29, 95 % CI 1.06-4.95; P = 0.03) were significant independent risk factors for joint symptoms.
2020 | Year | 03 | Month | 15 | Day |
2016 | Year | 04 | Month | 21 | Day |
Patients treated with anastorozole
Recruited after obtained informed consent
Arthralgia 166 (54.4 %)
Decrease of joint motion 104 (34.1 %)
Joint stiffness 182 (59.7 %)
Frequency of new or worsening from baseline of joint symptoms
Completed
2009 | Year | 07 | Month | 07 | Day |
2009 | Year | 07 | Month | 12 | Day |
2009 | Year | 08 | Month | 01 | Day |
2019 | Year | 12 | Month | 31 | Day |
The frequency of side effects will be evaluated by questionaries.
2009 | Year | 09 | Month | 06 | Day |
2020 | Year | 03 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002659
Research Plan | |
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Registered date | File name |
2020/03/15 | SAVS-JP申請(修正)09.8.8.doc |
Research case data specifications | |
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Registered date | File name |
2020/03/15 | 130405 ホルモン療法に伴う症状に関する問診票.xls |
Research case data | |
---|---|
Registered date | File name |
2020/03/15 | 130405 ホルモン療法に伴う症状に関する問診票.xls |