UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000002195 |
|---|---|
| Receipt number | R000002698 |
| Scientific Title | Functional analysis of mutations in calcium sensing receptor gene |
| Date of disclosure of the study information | 2009/07/14 |
| Last modified on | 2010/01/14 14:20:31 |
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Basic information
Public title
Functional analysis of mutations in calcium sensing receptor gene
Acronym
Functional analysis of mutant CaSR
Scientific Title
Functional analysis of mutations in calcium sensing receptor gene
Scientific Title:Acronym
Functional analysis of mutant CaSR
Region
| Japan |
Condition
Condition
The family of multiple endocrine neoplasia (MEN) type 2A
Classification by specialty
| Endocrinology and Metabolism |
Classification by malignancy
Others
Genomic information
YES
Objectives
Narrative objectives1
To identify the novel mutations in CaSR gene on MEN type 2A family, and to analyse those functions on Ca levels.
Basic objectives2
Bio-equivalence
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
1) Identification of novel mutations in CaSR gene
2) Functional analysis of Ca sensing ability in CaSR mutants
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| 70 | years-old | > |
Gender
Male and Female
Key inclusion criteria
Family member of MEN type 2A
Key exclusion criteria
Nothing but above
Target sample size
10
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Tatsuya Kondo |
Organization
Faculty of Medical and Pharmaceutical Sciences, Kumamoto University
Division name
Metabolic Medicine
Zip code
Address
1-1-1 Honjo, Kumamoto
TEL
+81-96-373-5169
Public contact
Name of contact person
| 1st name | |
| Middle name | |
| Last name | Tatsuya Kondo |
Organization
Faculty of Medical and Pharmaceutical Sciences, Kumamoto University
Division name
Metabolic Medicine
Zip code
Address
1-1-1 Honjo, Kumamoto
TEL
+81-96-373-5169
Homepage URL
t-kondo@gpo.kumamoto-u.ac.jp
Sponsor or person
Institute
Faculty of Medical and Pharmaceutical Sciences, Kumamoto University
Institute
Department
Personal name
Funding Source
Organization
Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Metabolic Medicine
Organization
Division
Category of Funding Organization
Self funding
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Address
Tel
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2009 | Year | 07 | Month | 14 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Terminated
Date of protocol fixation
| 2009 | Year | 07 | Month | 14 | Day |
Date of IRB
Anticipated trial start date
| 2009 | Year | 07 | Month | 01 | Day |
Last follow-up date
| 2010 | Year | 07 | Month | 01 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
1) Identification of novel CaSR mutations
2) Functional analysis of mutant CaSR
Management information
Registered date
| 2009 | Year | 07 | Month | 14 | Day |
Last modified on
| 2010 | Year | 01 | Month | 14 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002698
| Research Plan | |
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| Registered date | File name |
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| Registered date | File name |
| Research case data | |
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