Unique ID issued by UMIN | UMIN000002205 |
---|---|
Receipt number | R000002712 |
Scientific Title | Investigation about treatment of midnight hypertension in diabetes |
Date of disclosure of the study information | 2009/09/15 |
Last modified on | 2017/04/02 02:29:18 |
Investigation about treatment of midnight hypertension in diabetes
Investigation about treatment of midnight hypertension in diabetes
Investigation about treatment of midnight hypertension in diabetes
Investigation about treatment of midnight hypertension in diabetes
Japan |
hypertension in diabetes
Cardiology | Endocrinology and Metabolism |
Others
NO
To clarify the best combination of Ca antagonist and ARB in the treatment of hypertensive diabetes patients using ambulatory blood pressure monitoring
Safety,Efficacy
Exploratory
Pragmatic
Phase II
comparison of the anti-hypertensive effect through the 24 hrs
change in urinary albumin excretion ratio
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
4
Treatment
Medicine |
olmesartan 20 mg +amlodipine 5mg
once daily
olmesartan 20 mg + azelnidipine 16 mg
once daily
candesartan 8 mg or varsartan 80 mg + amlodipine 5mg
once daily
candesartan 8 mg or varsartan 80 mg + azelnidipine 16 mg
once daily
20 | years-old | <= |
79 | years-old | > |
Male and Female
diabetes patient having midnight hypertension
1) drug allergy to ARB or Ca antagonist
2) pregnant women or possible pregnant women
3) using anti-fugal drug or HIV protease inhibitor
4) bilateral renal artery stenosis or unilateral renal artery stenosis of remnant kidny
40
1st name | |
Middle name | |
Last name | Kazuhiko sakaguchi |
Department od Internal Medicine, Kobe University Graduate School of Medicine
Division of diabetes, metabolism and Endocrinology
7-5-1 Kusunoki-cho, Chuo-ku, Kobe
078-382-5861
kzhkskgc@med.kobe-u.ac.jp
1st name | |
Middle name | |
Last name | Kazuhiko sakaguchi |
Department od Internal Medicine, Kobe University Graduate School of Medicine
Division of diabetes, metabolism and Endocrinology
7-5-1 Kusunoki-cho, Chuo-ku, Kobe
078-382-5861
kzhkskgc@med.kobe-u.ac.jp
Division of diabetes, metabolism and Endocrinology
Department od Internal Medicine, Kobe University Graduate School of Medicine
none
Other
Japan
none
none
NO
2009 | Year | 09 | Month | 15 | Day |
Unpublished
Terminated
2009 | Year | 06 | Month | 03 | Day |
2009 | Year | 09 | Month | 01 | Day |
2013 | Year | 07 | Month | 15 | Day |
2009 | Year | 07 | Month | 15 | Day |
2017 | Year | 04 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002712
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |