Unique ID issued by UMIN | UMIN000002264 |
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Receipt number | R000002772 |
Scientific Title | Effects of Miglitol on Endothelial Vascular Reactivity in Type 2 Diabetic Patients with Coronary Heart Disease |
Date of disclosure of the study information | 2009/07/30 |
Last modified on | 2010/01/28 15:43:57 |
Effects of Miglitol on Endothelial Vascular Reactivity in Type 2 Diabetic Patients with Coronary Heart Disease
J-MACH
Effects of Miglitol on Endothelial Vascular Reactivity in Type 2 Diabetic Patients with Coronary Heart Disease
J-MACH
Japan |
Type 2 diabetic patients with coronary heart disease
Cardiology | Endocrinology and Metabolism |
Others
NO
To compare the postprandial effects of single administration of alph-glucosidase inhibitors on changing levels of endothelial function in type 2 diabetic patients with coronary heart disease
Efficacy
Confirmatory
Pragmatic
Not applicable
Endothelial function evaluated by plethysmography
blood glucose, serum insulin, lipid, oxidative stress marker, inflammatory marker, incretin
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
Numbered container method
3
Treatment
Medicine |
Miglitol 50mg
Voglibose 0.3mg
Placebo
20 | years-old | <= |
70 | years-old | > |
Male and Female
Type 2 diabetic patients with coronary heart disease. HbA1c <= 8% and casual blood glucose >= 200mg/dL.
Type 1 diabetes. Patients receiving insulin therapy. Patients with one of the following clinical conditions: severe liver dysfunction, severe renal dysfunction, congestive heart failure, acute coronary syndrome within 3 months, and other severe concomitant diseases. Patients who are judged inappropriate for entry into this study by the investigator.
12
1st name | |
Middle name | |
Last name | Kazunori Shimada |
Juntendo University School of Medicine
Department of Cardiovascular Medicine
2-1-1 Hongo Bunkyo-ku, Tokyo 113-8421 Japan
1st name | |
Middle name | |
Last name | Makoto Hiki |
Juntendo University School of Medicine
Department of Cardiovascular Medicine
2-1-1 Hongo Bunkyo-ku, Tokyo 113-8421 Japan
03-3813-3111
m-hiki@juntendo.ac.jp
Department of Cardiovascular Medicine, Juntendo University School of Medicine
Department of Cardiovascular Medicine, Juntendo University School of Medicine
Self funding
NO
2009 | Year | 07 | Month | 30 | Day |
Partially published
Completed
2007 | Year | 05 | Month | 11 | Day |
2007 | Year | 06 | Month | 01 | Day |
2009 | Year | 08 | Month | 01 | Day |
2009 | Year | 12 | Month | 01 | Day |
2009 | Year | 12 | Month | 01 | Day |
2009 | Year | 12 | Month | 01 | Day |
2009 | Year | 07 | Month | 28 | Day |
2010 | Year | 01 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002772
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