Unique ID issued by UMIN | UMIN000002423 |
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Receipt number | R000002967 |
Scientific Title | Assessment of pleiotropic and proteinuria reducing effect of irbesartan in chronic kidney disease patients |
Date of disclosure of the study information | 2009/09/07 |
Last modified on | 2021/10/05 12:44:11 |
Assessment of pleiotropic and proteinuria reducing effect of irbesartan in chronic kidney disease patients
Pleiotropic effect of irbesartan in chronic kidney disease patients
Assessment of pleiotropic and proteinuria reducing effect of irbesartan in chronic kidney disease patients
Pleiotropic effect of irbesartan in chronic kidney disease patients
Japan |
Chronic kidney disease stage 1-4
Medicine in general |
Others
NO
The purpose of the study is to estimate proteinuria reducing and pleiotropic effect of irbesartan in Japanese CKD patients.
Efficacy
The primary outcome is proteinuria reducing effect at four, twelve and twenty-four months after administration of the ARB case compared with at baseline.
The secondary outcome is the impact of irbesartan on adiponectin, leptin, IGF-1, hsCRP, IL-6, IL-10. TNF, at four, twelve and twenty-four months after administration of the ARB case compared with at baseline.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Treatment
Medicine |
irbesartan
20 | years-old | <= |
Not applicable |
Male and Female
1) Renal dysfunction: CKD stage 1-4
2) Expected survival time is more than 6 months
3) Aged 20 years over
4) Fully informed consent was obtained
1) Patients who has past history of adverse effect of taking another ARB
2) Pregnancy
3) Patients who has serious liver disease and coronary heart disease or nephrotic syndrome
4) Judged inappropriate for this study by the physicians
20
1st name | Hirokazu |
Middle name | |
Last name | Honda |
Showa University School of Medicine
Division of Nephrology , Depertment of Medicine
142-8666
1-5-8, Hatanodai, Shinagawaku, Tokyo, Japan
0337848533
hondah@med.showa-u.ac.jp
1st name | Hirokazu |
Middle name | |
Last name | Honda |
Showa University School of Medicine
Division of Nephrology Department of Medicine
142-8666
1-5-8, Hatanodai, Shinagawa-ku, Tokyo
03-3784-8533
hondah@med.showa-u.ac.jp
Division of Nephrology Department of Medicine, Showa University School of Medicine
Division of Nephrology Department of Medicine, Showa University School of Medicine
Self funding
Ethics Committee for Research Involving Human Subjects at Showa University School of Medicine
1-5-8, Hatanodai, Shinagawa-ku, Tokyo
03-3784-8022
mkyoumu@ofc.showa-u.ac.jp
NO
2009 | Year | 09 | Month | 07 | Day |
Unpublished
Open public recruiting
2009 | Year | 08 | Month | 01 | Day |
2009 | Year | 09 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2009 | Year | 09 | Month | 01 | Day |
2021 | Year | 10 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000002967
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