Unique ID issued by UMIN | UMIN000002555 |
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Receipt number | R000003121 |
Scientific Title | Early effects of administrations of Roxatidine(H2RA) and Omeprazole(PPI) on intragastric pH |
Date of disclosure of the study information | 2009/09/30 |
Last modified on | 2010/06/15 21:36:16 |
Early effects of administrations of Roxatidine(H2RA) and Omeprazole(PPI) on intragastric pH
Early effects of administrations of H2RA and PPI on intragastric pH
Early effects of administrations of Roxatidine(H2RA) and Omeprazole(PPI) on intragastric pH
Early effects of administrations of H2RA and PPI on intragastric pH
Japan |
healty adult men
Gastroenterology |
Others
NO
The ideal medication for treatment of acid related diseases should have a rapid onset of action to promote hemostasis and symptoms.
Proton pump inhibitors is used for GERD and gastric ulcer etc.
The aim of our study was to investigate the inhibitory effects on gastric acid secretion after single administrations of Roxatidine 75mg and Omeprazole 20mg.
Pharmacodynamics
intragastric pH by pH meter attached to the antimony pH electrode
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
Uncontrolled
2
Treatment
Medicine |
Omeplazole 20mg
Roxatidine 75mg
20 | years-old | <= |
Not applicable |
Male
Patient who fills everything the following
1) Helicobacter pylori-negative male Patient
2) Patient of 20 years or more
3) Patient who gives written informed consent
The patient who collides with either the following assumes that it doesn't put it in to the examination
1) Drug allergy
2) Patient who took medicine that influences movement and function of digestive tract such as proton pump inhibitor, H2 blocker, and NSAIDs within 4 weeks
10
1st name | |
Middle name | |
Last name | Atsushi Nakajima |
Yokohama City University Graduate School of Medicine
Gastroenterology Division
3-9 Fuku-ura, Kanagawa-ku, Yokohama, Japan
045-787-2640
1st name | |
Middle name | |
Last name | Masahiko Inamori |
Yokohama City University Graduate School of Medicine
Gastroenterology Division
3-9 Fuku-ura, Kanagawa-ku, Yokohama, Japan
045-787-2640
inamorim@med.yokohama-cu.ac.jp
Gastroenterology Division, Yokohama City University Graduate School of Medicine
none
Other
NO
横浜市立大学大学院(神奈川県)
2009 | Year | 09 | Month | 30 | Day |
Unpublished
Completed
2009 | Year | 09 | Month | 30 | Day |
2009 | Year | 10 | Month | 01 | Day |
2014 | Year | 09 | Month | 01 | Day |
2009 | Year | 09 | Month | 28 | Day |
2010 | Year | 06 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000003121
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