Unique ID issued by UMIN | UMIN000002704 |
---|---|
Receipt number | R000003296 |
Scientific Title | Pharmacotherapy for behavioral symptoms of frontotemporal dementia |
Date of disclosure of the study information | 2009/11/04 |
Last modified on | 2009/11/03 14:23:18 |
Pharmacotherapy for behavioral symptoms of frontotemporal dementia
Pharmacotherapy for frontotemporal dementia
Pharmacotherapy for behavioral symptoms of frontotemporal dementia
Pharmacotherapy for frontotemporal dementia
Japan |
frontotemporal dementia
Neurology | Psychiatry |
Others
NO
Behavioral symptoms of frontotemporal dementia (FTD) place a heavy burden on the caregivers. Although used to control symptoms, antipsychotic drugs have adverse effects that lower their ability to perform activities of daily living (ADL), and reduce their quality of life (QOL). Iwasaki et al. reported the effect of Yokukansan to behavioral and psychological symptoms of dementia (BPSD). Therefore, we evaluate the efficacy and safety of Yokukansan as a treatment of behavioral symptoms of FTD.
Safety,Efficacy
Confirmatory
Pragmatic
Phase I,II
Neuropsychiatric Inventory (NPI)
Stereotypy Rating Inventory (SRI)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
dose of 7.5 g/day Yokukansan
50 | years-old | <= |
90 | years-old | >= |
Male and Female
FTD patients diagnosed according to Consensus guidelines of FTD (Neurology 1998; 51: 1546-1554)
(1) delirium due to metabolic intoxication and drug use; (2) alcoholism, stroke, depression, manic state, and schizophrenia before the onset of FTD; (3) previous use of Yokukansan, major tranquilizers, and antidepressants; (4) neoplastic disease and acute inflammation
25
1st name | |
Middle name | |
Last name | Takemi Kimura |
NHO Kikuchi Hospital
Division of Clinical Research
208 Fukuhara, Koshi, Kumamoto
1st name | |
Middle name | |
Last name |
NHO Kikuchi Hospital
Division of Clinical Research
tkimura@kikuti.hosp.go.jp
NHO Kikuchi Hospital
NHO Kikuchi Hospital
NO
2009 | Year | 11 | Month | 04 | Day |
Partially published
Completed
2008 | Year | 04 | Month | 01 | Day |
2008 | Year | 11 | Month | 01 | Day |
2009 | Year | 10 | Month | 01 | Day |
2009 | Year | 11 | Month | 03 | Day |
2009 | Year | 11 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000003296
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |