Unique ID issued by UMIN | UMIN000002718 |
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Receipt number | R000003309 |
Scientific Title | An open label multi facilities cooperation randomized control trial for prevention Evolution of Diabetic nephrOpathy by Olmesartan |
Date of disclosure of the study information | 2009/11/09 |
Last modified on | 2010/04/16 11:54:53 |
An open label multi facilities cooperation randomized control trial for prevention Evolution of Diabetic nephrOpathy by Olmesartan
Olmesartan prevents Evolution of Diabetic nephrOpathy(OEDO-STUDY)
An open label multi facilities cooperation randomized control trial for prevention Evolution of Diabetic nephrOpathy by Olmesartan
Olmesartan prevents Evolution of Diabetic nephrOpathy(OEDO-STUDY)
Japan |
Hypertensive type2 diabetic patients without nephropathy
Medicine in general | Cardiology | Endocrinology and Metabolism |
Nephrology |
Others
NO
Benefits of olmesartan treatment for prevention of diabetic nephropathy
-L-PGDS as a biomarker of diabetic nephropathy-
Efficacy
an incrase of albuminuria
1) number of patients with above 30mg/gCr albuminuria
2) an increase of urinary L-PGDS excretions
Interventional
Parallel
Randomized
Open -but assessor(s) are blinded
Active
2
Treatment
Medicine |
olmesartan10-40mg once a day for six months
amlodipine 2.5-10mg once a day for six months
20 | years-old | <= |
Not applicable |
Male and Female
Hypertensive type2 diabetic patients without nephropathy
Outpatients aged 20 years or moreover
SBP is >= 130mgHg or DBP is >= 80mgHg
Type2 diabetes
Albuminuria is below 30mg/gCr
Untreated hypertensive patients or patients treated with CaB alone
Agreement
SBP >=160mgHg or DBP >=100mgHg.
Secondary hypertension
Severe hepatic dysfunction or renal damage.
Severe adverse effects with study drugs.
Severs clincal condition due to tumors et al.
Inappropriate cases based on the descision by responsible doctors .
120
1st name | |
Middle name | |
Last name | Uehara yoshio |
Kyoritsu Women's University
Faculty of Home Economics
2-2-1 Hitotsubashi, Chiyoda, Tokyo
1st name | |
Middle name | |
Last name |
Kyoritsu Women's University
Faculty of Home Economics
Jyoto Hypertension Research Group
None
Self funding
NO
2009 | Year | 11 | Month | 09 | Day |
Unpublished
Enrolling by invitation
2009 | Year | 07 | Month | 13 | Day |
2011 | Year | 03 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2009 | Year | 11 | Month | 05 | Day |
2010 | Year | 04 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000003309
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