Unique ID issued by UMIN | UMIN000003166 |
---|---|
Receipt number | R000003375 |
Scientific Title | Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Extended JAPAN-ACS) |
Date of disclosure of the study information | 2010/02/12 |
Last modified on | 2012/04/17 11:54:17 |
Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Extended JAPAN-ACS)
Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Extended JAPAN-ACS)
Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Extended JAPAN-ACS)
Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Extended JAPAN-ACS)
Japan |
acute coronary syndrome
Cardiology |
Others
NO
To verify the relationship between coronary plaque regression and cardiovascular prevention in long term follow up of the JAPAN-ACS study. In addition, the objectives of this study are to evaluate the effect of serum lipid levels or different type of statins on cardiovascular prevention.
Efficacy
Confirmatory
Pragmatic
Not applicable
Occurrence of one offollowing events (composite endpoint)
1.Cardiovascular death
2.Non-fatal Myocardial Infarction (MI)
3.Non-fatal Cerebral Infarction (CI)4.Unstable angina requiring urgent hospitalizations
1.Composite cardiovascular events
Occurrence of one of following events
Cardiovascular death, Non-fatal MI, Non-fatal CI, Unstable angina requiring hospitalizations, Ischemia-driven coronary revascularization except target lesion revascularization (TLR)
2.Composite coronary heart disease events
Occurrence of one of following events
Coronary heart disease (CHD) death, Non-fatal MI, Unstable angina requiring urgent hospitalizations, Ischemia-driven coronary revascularization except TLR.
3.Composite cerebrovascular events
Occurrence of one of following events
Fatal and Non-fatal stroke, Transient ischemic attack (TIA) requiring hospitalizations.
4.Death events
Occurrence of each following events
All-cause mortality
Cardiovascular death
Cardiac death
CHD death
5.Heart disease events
Occurrence of each following events
Fatal and Non-fatal MI
Non-procedure related MI
Procedure related MI
Unstable angina requiring urgent hospitalizations
Resuscitated cardiac arrest
Hospitalization for heart failure
PCI or CABG
(1)All events of PCI or CABG
(a)TLR
(b)non-TLR
(2)Ischemia-driven PCI or CABG
(a)TLR
(b)non-TLR
6.Cerebrovascular events
Occurrence of each following events
Fatal and Non-fatal stroke
Fatal and Non-fatal CI
(1) Non-procedure related CI
(2) Procedure related CI
Fatal and Non-fatal cerebral hemorrhage
Hospitalization for TIA
7.The other events
Occurrence of each following events
Operation for or rupture of aortic aneurysm
Revascularization for peripheral arterial disease (PAD)
Carotid artery stenting (CAS) or carotid endarterectomy (CEA)
Aortic dissection
Deep vein thrombosis (DVT) or pulmonary thromboembolism (PTE)
New occurrence of malignant tumor
Operation for aortic stenosis
Observational
Not applicable |
Not applicable |
Male and Female
Patients who were underwent coronary intravascular ultrasound (IVUS) evaluation both at baseline and the follow up period, and whose IVUS data were analyzable in the JAPAN-ACS study.
none
252
1st name | |
Middle name | |
Last name | Masunori Matsuzaki |
Yamaguchi University Graduate School of Medicine
Division of Cardiology, Department of Medicine and Clinical Science
1-1-1 Minamikogushi, Ube-city, Yamaguchi, 755-8505
0836-22-2248
1st name | |
Middle name | |
Last name | Yumika Fujino |
Cardiovascular Research Promotion Unit
Cardiovascular Research Promotion Unit
15, Shimogamo Morimoto-cho, Sakyo-ku, Kyoto, JAPAN 606-0805
075-781-1107
http://www.japan-acs.or.jp/
japan-acs.seiken@midinfo.co.jp
Research Institute for Production Development
Japan Heart Foundation
Non profit foundation
Japan
NO
NTT 東日本札幌病院(北海道)、財団法人厚生会仙台厚生病院(宮城県)、秋田県成人病医療センター(秋田県)、順天堂大学医学部附属浦安病院(千葉県)、国家公務員共済組合連合会虎の門病院、順天堂大学医学部附属順天堂医院、東京大学医学部附属病院(東京都)、公立大学法人横浜市立大学附属市民総合医療センター(神奈川県)、岐阜県総合医療センター(岐阜県)、順天堂大学医学部附属静岡病院(静岡県)、愛知医科大学病院、愛知県厚生農業協同組合連合会安城更生病院、名古屋第一赤十字病院、藤田保健衛生大学病院、(愛知県)、市立四日市病院(三重県)、京都大学医学部附属病院(京都府)、大阪市立総合医療センター、国立循環器病センター(大阪府)、独立行政法人労働者健康福祉機構関西労災病院(兵庫県)、和歌山県立医科大学附属病院(和歌山県)、岡山赤十字病院、財団法人倉敷中央病院(岡山県)、医療法人あかね会土谷総合病院、広島市立安佐市民病院、広島市立広島市民病院(広島県)、綜合病院社会保険徳山中央病院、山口大学医学部附属病院(山口県)、独立行政法人国立病院機構浜田医療センター(島根県)、愛媛県立中央病院(愛媛県)、社会保険小倉記念病院、福岡大学病院(福岡県)、社会福祉法人恩賜財団済生会熊本病院(熊本県)、独立行政法人国立病院機構鹿児島医療センター(鹿児島県)
2010 | Year | 02 | Month | 12 | Day |
Published
http://www.jstage.jst.go.jp/article/circj/76/4/76_825/_article
Completed
2010 | Year | 02 | Month | 08 | Day |
2010 | Year | 11 | Month | 01 | Day |
2011 | Year | 03 | Month | 01 | Day |
2011 | Year | 05 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2011 | Year | 12 | Month | 01 | Day |
To verify the relationship between coronary plaque regression and cardiovascular prevention.
2010 | Year | 02 | Month | 10 | Day |
2012 | Year | 04 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000003375
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |