Unique ID issued by UMIN | UMIN000002839 |
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Receipt number | R000003469 |
Scientific Title | The efficacy and safety of autologous gamma/delta T cell transfer therapy after resection of stage2A (T2N0,T3N0) esophageal cancer |
Date of disclosure of the study information | 2009/12/03 |
Last modified on | 2016/01/29 18:00:29 |
The efficacy and safety of autologous gamma/delta T cell transfer therapy after resection of stage2A (T2N0,T3N0) esophageal cancer
Autologous gamma/delta T cell therapy after resection of esophageal cancer
The efficacy and safety of autologous gamma/delta T cell transfer therapy after resection of stage2A (T2N0,T3N0) esophageal cancer
Autologous gamma/delta T cell therapy after resection of esophageal cancer
Japan |
Esophageal cancer
Gastrointestinal surgery |
Malignancy
NO
To investigate efficacy and safety of autologous gamma/delta T cell transfer therapy after curative resection for esophageal cancer
Safety,Efficacy
Exploratory
Pragmatic
Not applicable
Recurrence rate
Recurrence-free survival
Overall survival
Survival rate
Response of tumor-related markers
Immunological responses
Safety
Interventional
Single arm
Non-randomized
Open -no one is blinded
Historical
1
Treatment
Maneuver |
Gamma/delta T cells are injected on day0, day7, day14, day21, day35, day49, day63, day77.
20 | years-old | <= |
Not applicable |
Male and Female
Esophageal cancer patients who received curative resection and are histopathologically diagnosed as T2N0 or T3N0:
-Performance status is 0-2;
-20 years or more;
-No serious abnormality in heart, lung, bone marrow, liver, and renal functions.
Patients who have:
-Pulmonary fibrosis or interstitial pneumonia, including their history or predisposition;
-Serious drug allergy;
-Difficult infections to control;
-Serious cardiac diseases;
-Active enteritis;
-Active autoimmune diseases;
-Other cancers;
-Continuous systemic administration of steroids and/or immunosuppressants within 4 weeks.
15
1st name | |
Middle name | |
Last name | Yasuyuki Seto |
The University of Tokyo Hospital
Gastrointestinal Surgery Division
7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
03-5800-9730
seto-tky@umin.ac.jp
1st name | |
Middle name | |
Last name | Kazuhiro Kakimi |
The University of Tokyo, Graduate School of Medicine
Department of Immunotherapeutics
7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
03-5805-3161
immunotherapy-admin@umin.ac.jp
The University of Tokyo Hospital
Medinet Co.,Ltd.
Profit organization
Japan
NO
東京大学医学部附属病院(東京都)
2009 | Year | 12 | Month | 03 | Day |
Published
No patient enrolled.
Completed
2009 | Year | 11 | Month | 09 | Day |
2009 | Year | 12 | Month | 01 | Day |
2015 | Year | 07 | Month | 31 | Day |
2009 | Year | 12 | Month | 03 | Day |
2016 | Year | 01 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000003469
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