UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000003426 |
|---|---|
| Receipt number | R000004145 |
| Scientific Title | Genomic and functional evaluation of perivascular adipose tissue. |
| Date of disclosure of the study information | 2010/04/05 |
| Last modified on | 2014/03/27 16:01:26 |
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Basic information
Public title
Genomic and functional evaluation of perivascular adipose tissue.
Acronym
Genomic and functional evaluation of perivascular adipose tissue.
Scientific Title
Genomic and functional evaluation of perivascular adipose tissue.
Scientific Title:Acronym
Genomic and functional evaluation of perivascular adipose tissue.
Region
| Japan |
Condition
Condition
Atherosclerosis
Classification by specialty
| Cardiology |
Classification by malignancy
Others
Genomic information
YES
Objectives
Narrative objectives1
To clarify the influence of perivascular adipose tissue to the formation of atherosclerosis of patients with cardiovascular disease.
Basic objectives2
Others
Basic objectives -Others
To identify the vasodilatative molecule from perivascular adipose tissue
Trial characteristics_1
Trial characteristics_2
Developmental phase
Assessment
Primary outcomes
Adipocytokines from perivascular adipose tissue.
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| 20 | years-old | <= |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Patients who undergo cardiovascular surgery in Tokushima University Hospital, Tokushima Prefectural Central Hospital, Ehime Prefectural Central Hospital, Sakakibara Memorial Hospital.
Key exclusion criteria
Patients from whom written informed consent was not obtained.
Target sample size
100
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Masataka Sata |
Organization
University of Tokushima Graduate School, Institute of Health Bioscience.
Division name
Department of cardiovascular medicine
Zip code
Address
3-18-15 Kuramoto-cho, Tokushima-city, Tokushima 770-8503, Japan
TEL
088-633-7851
masataka.sata@tokushima-u.ac.jp
Public contact
Name of contact person
| 1st name | |
| Middle name | |
| Last name | Michio Shimabukuro |
Organization
University of Tokushima Graduate School, Institute of Health Bioscience.
Division name
Department of cardiovascular medicine
Zip code
Address
3-18-15 Kuramoto-cho, Tokushima-city, Tokushima 770-8503, Japan
TEL
088-633-7851
Homepage URL
mshimabukuro-ur@umin.ac.jp
Sponsor or person
Institute
Department of Cardiovascular Medicine, University of Tokushima Graduate School, Institute of Health Bioscience
Institute
Department
Personal name
Funding Source
Organization
Knowledge Cluster and New Research Area
Organization
Division
Category of Funding Organization
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Address
Tel
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
徳島大学医学部・歯学部附属病院
Other administrative information
Date of disclosure of the study information
| 2010 | Year | 04 | Month | 05 | Day |
Related information
URL releasing protocol
Publication of results
Unpublished
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2008 | Year | 09 | Month | 22 | Day |
Date of IRB
Anticipated trial start date
| 2008 | Year | 09 | Month | 01 | Day |
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
Pare samples are obtained from epicardial and subcutaneous adipose tissue during elective cardiac surgery. Inflammatory
cell infiltration is investigated by immunohistochemical staining. Expression of adipocytokines was evaluated by real-time
quantitative reverse transcription-polymerase chain reaction.
Management information
Registered date
| 2010 | Year | 04 | Month | 01 | Day |
Last modified on
| 2014 | Year | 03 | Month | 27 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004145
| Research Plan | |
|---|---|
| Registered date | File name |
| Research case data specifications | |
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| Registered date | File name |
| Research case data | |
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| Registered date | File name |
