UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000003462 |
|---|---|
| Receipt number | R000004180 |
| Scientific Title | Signal transduction of heat shock protein in hepatitis and hepatocellular carcinoma |
| Date of disclosure of the study information | 2010/04/08 |
| Last modified on | 2023/04/17 10:03:58 |
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Basic information
Public title
Signal transduction of heat shock protein in hepatitis and hepatocellular carcinoma
Acronym
Signal transduction of HSP in hepatitis and HCC
Scientific Title
Signal transduction of heat shock protein in hepatitis and hepatocellular carcinoma
Scientific Title:Acronym
Signal transduction of HSP in hepatitis and HCC
Region
| Japan |
Condition
Condition
hepatitis and hepatocellular carcinoma
Classification by specialty
| Hepato-biliary-pancreatic medicine | Hepato-biliary-pancreatic surgery |
Classification by malignancy
Malignancy
Genomic information
NO
Objectives
Narrative objectives1
This project aims to elucidate the roles of HSP in hepatitis and in hepatocellular carcinoma development.
Basic objectives2
Others
Basic objectives -Others
The expression and modification of the heat shock proteins and the proteins of related signal transduction in hepatitis and hepatocellular carcinoma are examined.
Trial characteristics_1
Exploratory
Trial characteristics_2
Pragmatic
Developmental phase
Not applicable
Assessment
Primary outcomes
HSPs and the related proteins expression in the liver tissues of chronic liver disease or HCC patients .
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
The patients wih chronic hepatitis or hepatocellular carcinoma
Key exclusion criteria
None
Target sample size
300
Research contact person
Name of lead principal investigator
| 1st name | Rie |
| Middle name | |
| Last name | Matsushima-Nishiwaki |
Organization
Gifu University Graduate School of Medicine
Division name
Department of Pharmacology
Zip code
5001194
Address
Yanagito 1-1, Gifu, Gifu, Japan 501-1194
TEL
058-230-6214
nishiwaki.rie.r7@f.gifu-u.ac.jp
Public contact
Name of contact person
| 1st name | Rie |
| Middle name | |
| Last name | Nishiwaki-Matsushima |
Organization
Gifu University Graduate School of Medicine
Division name
Department of Pharmacology
Zip code
5001194
Address
1-1 Yanagito, Gifu
TEL
058-230-6217
Homepage URL
nishiwaki.rie.r7@f.gifu-u.ac.jp
Sponsor or person
Institute
Department of Pharmacology, Gifu University Graduate School of Medicine
Institute
Department
Personal name
Funding Source
Organization
Grants in Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture of Japan
Organization
Division
Category of Funding Organization
Japanese Governmental office
Nationality of Funding Organization
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Medical research ethics committee of Gifu University Graduate School of Medicine
Address
1-1 Yanagido, Gifu, Gifu, Japan
Tel
058-230-6000
gjme00004@jim.gifu-u.ac.jp
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
Other administrative information
Date of disclosure of the study information
| 2010 | Year | 04 | Month | 08 | Day |
Related information
URL releasing protocol
Publication of results
Partially published
Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Open public recruiting
Date of protocol fixation
| 2010 | Year | 02 | Month | 15 | Day |
Date of IRB
| 2010 | Year | 03 | Month | 02 | Day |
Anticipated trial start date
| 2010 | Year | 04 | Month | 01 | Day |
Last follow-up date
| 2029 | Year | 03 | Month | 31 | Day |
Date of closure to data entry
Date trial data considered complete
Date analysis concluded
Other
Other related information
The tissues are obtained by surgical resection or percutaneous liver biopsy from the patients with hepatitis or hepatocellular carcinoma at the Department of Surgery, Ogaki Municipal Hospital. The resected tissues were snapfrozen in liquid nitrogen and then stored at -80 degree until used for the analysis.
Management information
Registered date
| 2010 | Year | 04 | Month | 08 | Day |
Last modified on
| 2023 | Year | 04 | Month | 17 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004180
| Research Plan | |
|---|---|
| Registered date | File name |
| Research case data specifications | |
|---|---|
| Registered date | File name |
| Research case data | |
|---|---|
| Registered date | File name |
