Unique ID issued by UMIN | UMIN000003868 |
---|---|
Receipt number | R000004286 |
Scientific Title | Effect of acarbose on amelioration of endothelial function evaluated by FMD in type 2 diabetic patients. |
Date of disclosure of the study information | 2011/03/31 |
Last modified on | 2017/01/08 11:13:29 |
Effect of acarbose on amelioration of endothelial function evaluated by FMD in type 2 diabetic patients.
Acarbose-FMD clinical trial
Effect of acarbose on amelioration of endothelial function evaluated by FMD in type 2 diabetic patients.
Acarbose-FMD clinical trial
Japan |
type 2 diabetes mellitus
Endocrinology and Metabolism |
Others
YES
To compare the protective effects of acarbose and voglibose on endothelial function evalutaed by FMD in type 2 diabetes patients.
Efficacy
Confirmatory
Pragmatic
Not applicable
Flow Mediated Dilation test
HbA1c, fasting blood glucose/triglyceride and postprandial (2h) blood glucose/triglyceride, LDL-cholesterol, HDL-cholesterol, urinary albumin extraction, body weight, blood pressure
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Prevention
Medicine |
acarbose 150-300 mg/day
voglibose 0.9 mg/day
20 | years-old | <= |
Not applicable |
Male and Female
1)Type 2 diabetic patients who have been treated with voglibose 0.9 mg/day for 3 months or more.
2)HbA1c of 6.5%(NGSP) or more.
1)Patients with ACS within 6 months
2)Patie nts treating with insulin
3)Patients who have undergone a gastrectomy or abdominal surgery
4)Patients with sever hepatic dysfunction or renal dysfunction
5)Patients with serious ketosis, diabetic coma, pre-coma
6)Patients with sever infection, pre-/after recent operation , serious trauma
7)Patients with gastrointestinal disorders such as diarrhea and vomitting
8)Patients with history of sensitivity to acarbose
9)Women who are pregnant or with a possibility of pregnancy
10)Other patients whom the investigator deems unsuitable for inclusion in this study
70
1st name | |
Middle name | |
Last name | Eitaro Nakashima |
Chubu Rousai Hospital
Dept. of Diabetes and Endocrinology
1-10-6 Koumei, Minato-ku, Nagoya
+81-52-652-5511
eitaro@med.nagoya-u.ac.jp
1st name | |
Middle name | |
Last name | Eitaro Nakashima |
Chubu Rousai Hospital
Dept. of Diabetes and Endocrinology
1-10-6 Koumei, MInato--ku, Nagoya
052-652-5511
eitaro@med.nagoya-u.ac.jp
Chubu Rousai Hospital
Chubu Rosai Hospital
Self funding
Japan
None
None
NO
中部労災病院(愛知県)
2011 | Year | 03 | Month | 31 | Day |
Unpublished
Completed
2010 | Year | 03 | Month | 31 | Day |
2010 | Year | 07 | Month | 01 | Day |
2011 | Year | 07 | Month | 01 | Day |
2011 | Year | 08 | Month | 01 | Day |
2011 | Year | 12 | Month | 01 | Day |
2011 | Year | 12 | Month | 01 | Day |
2010 | Year | 07 | Month | 05 | Day |
2017 | Year | 01 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004286
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |