Unique ID issued by UMIN | UMIN000003846 |
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Receipt number | R000004631 |
Scientific Title | Effect of ARB and diuretics combination therapy on home blood pressure by using telemedicine system |
Date of disclosure of the study information | 2010/06/30 |
Last modified on | 2010/07/01 15:57:16 |
Effect of ARB and diuretics combination therapy on home blood pressure by using telemedicine system
PRETTY HOME TRIAL
Effect of ARB and diuretics combination therapy on home blood pressure by using telemedicine system
PRETTY HOME TRIAL
Japan |
Hypertension
Cardiology | Endocrinology and Metabolism | Nephrology |
Others
NO
The aim of this study is to evaluate the effect of ARB and diuretics combination therapy and high-dose ARB on home blood pressure by using telemedicine system. The hypertensive patients (Over 140/90 mmHg) treated with 50 mg dose of Losartan were recruited in this study. These patients were devited into two groups as follows; one group is treated with 50mg dose of Losartan plus 12.5mg dose of Hydrochlorthiaside, and the other group is treated with 100mg dose of Losrtan. To compare the efficacy and safety of combinatiion therapy of ARB plus low dose diuretics vs. high-dose ARB, home blood pressure of these patients were monitored by telemedicine system.
Safety,Efficacy
Confirmatory
Pragmatic
Phase IV
Moning blood pressure
Evening blood pressure
Insulin sensitivity
Metabolic factora
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
YES
NO
Institution is not considered as adjustment factor.
NO
Central registration
2
Treatment
Medicine |
Preminent treated group
(Losartan 50mg+Hydrochrolthiazide 12.5mg)
NLosartan 100mg
20 | years-old | <= |
80 | years-old | > |
Male and Female
Blood pressure over 140/90 mmHg treated with 50mg dose of Losartann
Secondary Hypertension
Pregnancy
Heart Failure with NYHA stage III
ESRD patients Cr over 2.0
50
1st name | |
Middle name | |
Last name | Hidetomo Nakamoto |
Saitama Medical University
General Internal Medicine
38Morohongo, Moroyamamachi, Iruma-gun, Saitama350-0451, Japan
049-276-1667
1st name | |
Middle name | |
Last name | Hidetomo Nakamoto |
Saitama Medical University
General Internal Medicine
38Morohongo, Moroyama-machi, Iruma-gun, Saitama
049-276-1667
nakamo_h@saitama-med.ac.jp
Department of General Internal Medicine, Saitama Medical School
Department of General Internal Medicine, Saitama Medical School
Self funding
Japan
NO
埼玉医科大学病院
2010 | Year | 06 | Month | 30 | Day |
Unpublished
Preinitiation
2010 | Year | 06 | Month | 01 | Day |
2010 | Year | 07 | Month | 01 | Day |
2011 | Year | 07 | Month | 01 | Day |
2011 | Year | 07 | Month | 01 | Day |
2011 | Year | 08 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2010 | Year | 06 | Month | 30 | Day |
2010 | Year | 07 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004631
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