Unique ID issued by UMIN | UMIN000003857 |
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Receipt number | R000004642 |
Scientific Title | The effects of betablocker for treatment of chronic atrial fibrillation in patients with hypertension. |
Date of disclosure of the study information | 2010/07/01 |
Last modified on | 2010/07/01 22:01:07 |
The effects of betablocker for treatment of chronic atrial fibrillation in patients with hypertension.
The effects of betablocker for treatment of chronic atrial fibrillation in patients with hypertension.
The effects of betablocker for treatment of chronic atrial fibrillation in patients with hypertension.
The effects of betablocker for treatment of chronic atrial fibrillation in patients with hypertension.
Japan |
Atrial fibrillation
Cardiology |
Others
NO
To compare the effects of a carvedilol and a bisoplol for treatment of chronic atrial fibrillation in patients with hypertension.
Safety,Efficacy
1. Subjective symptom: Frequency of palpitation
2. Objective symptom: New York Heart Association (NYHA) classification of cardiac performance, BP, HR
3. Laboratory test: Blood biochemical findings include BNP
4. Physiological laboratory: ambulatory electrocardiography, cardiac ultrasonography
5. Adverse event
Interventional
Cross-over
Non-randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
Carvedilol 2.5-20 mg/day, 3 months
Bisoprolol 2.5-5 mg/day, 3 months
20 | years-old | <= |
75 | years-old | > |
Male and Female
1) Patient who has either of chronic atrial fibrillation and hypertension.
2) Patients who are aged 20 years or older and less than 75 years at the entry.
3) Patients who have administred carvedilol or bisoprolol over 3 months.
4) Patients with left ventricular ejection fraction > 40%, and without decompensated heart failure.
1) Patients with contraindication to betablockers.
2) Patients with a history of unstable angina pectoris or myocardial infarction within 3 months.
3) Judgment by attending physician that patient participation would be inappropriate.
40
1st name | |
Middle name | |
Last name | Makoto Kodama |
Niigata University Graduate School of Medical and Dental Sciences
Division of Cardiology
1-757 Asahimachi-dori, Chuo-ku, Niigata
1st name | |
Middle name | |
Last name | Hiroaki Obata |
Niigata University Graduate School of Medical and Dental Sciences
Division of Cardiology
1-757 Asahimachi-dori, Chuo-ku, Niigata
Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences
None
Self funding
NO
2010 | Year | 07 | Month | 01 | Day |
Unpublished
Open public recruiting
2010 | Year | 06 | Month | 29 | Day |
2010 | Year | 07 | Month | 01 | Day |
2010 | Year | 07 | Month | 01 | Day |
2010 | Year | 07 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004642
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