Unique ID issued by UMIN | UMIN000004028 |
---|---|
Receipt number | R000004843 |
Scientific Title | Multicenter prospective Study to determine the efficacy of Strontium-89 for palliation of painful bone metastases in cancer patients |
Date of disclosure of the study information | 2010/08/10 |
Last modified on | 2023/08/23 12:15:45 |
Multicenter prospective Study to determine the efficacy of Strontium-89 for palliation of painful bone metastases in cancer patients
PMS-89
Multicenter prospective Study to determine the efficacy of Strontium-89 for palliation of painful bone metastases in cancer patients
PMS-89
Japan |
painful bone metastases
Radiology |
Malignancy
NO
To evaluate the palliative effect of sorontium-89 for painful bone metastases
Efficacy
Exploratory
Pragmatic
Not applicable
Response rate of palliative efficacy based on pain score recorded by patients
Prognostic factor of palliative effect
QOL
Safety
Observational
Not applicable |
Not applicable |
Male and Female
1) Histologically/cytologically proven solid tumor
2) Multiple bone metastases consisted with positive site of bone scintigram
3) Baseline pain score was 3 or more.
4) Patient was obtained insufficient effect by analgesics
5) Patient can not adapt to EBRT
6) Life expectancy>=1 month
7) Adequate haematological function:
- Haemoglobin>=9g/dl
- WBC count>=3,000/mm3
- Platelets>=75,000/mm3
8) Written informed consent
1) severe myelosupppression
2) marked fall of hematological function
3) Administration of Sr-89 within previous 3 months
4) DIC
5) Severe renal disfunction
6) Multiple myeloma
7) Pregnancy
8) Any condition, which, in the opinion of the investigator, might interfere with the evaluation of the study objectives
200
1st name | Makoto |
Middle name | |
Last name | Hosono |
Kindai University Faculty of Medicine
Institute of Advanced Clinical Medicine
589-8511
377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan
072-366-0221
hosono@med.kindai.ac.jp
1st name | Makoto |
Middle name | |
Last name | Hosono |
Kindai University Hospital
Institute of Advanced Clinical Medicine
589-8511
377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan
072-366-0221
hosono@med.kindai.ac.jp
PMS-89 Study Group
None
Self funding
None
PMS-89
Kindai University Hospital
377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan
072-366-0221
hosono@med.kindai.ac.jp
NO
近畿大学医学部附属病院(大阪府)
旭川医科大学(北海道)
大阪医科大学附属病院(大阪府)
大阪府立成人病センター(大阪府)
岡山大学(岡山県)
金沢大学附属病院(石川県)
川崎医科大学(岡山県)
京都市立病院(京都府)
市立堺病院(大阪府)
慶応義塾大学病院(東京都)
神戸大学医学部附属病院(兵庫県)
公立松任石川中央病院(石川県)
聖隷三方原病院(静岡県)
仙台厚生病院(宮城県)
高岡市民病院(富山県)
土浦協同病院(茨城県)
天理よろづ相談所病院(奈良県)
東京医科大学病院(東京都)
東京医療センター(東京都)
東京慈恵会医科大学附属(東京都)
長崎市立市民病院(長崎県)
長野赤十字病院(長野県)
奈良県立大学(奈良県)
西神戸医療センター(兵庫県)
山形大学医学部附属病院(山形県)
2010 | Year | 08 | Month | 10 | Day |
Unpublished
Completed
2010 | Year | 02 | Month | 01 | Day |
2009 | Year | 12 | Month | 10 | Day |
2010 | Year | 02 | Month | 01 | Day |
2015 | Year | 10 | Month | 05 | Day |
2015 | Year | 12 | Month | 25 | Day |
To extract the prognostic factor of palliative efficacy
To evaluate the effect of QOL
To evaluate the safety
2010 | Year | 08 | Month | 10 | Day |
2023 | Year | 08 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004843
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