Unique ID issued by UMIN | UMIN000004152 |
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Receipt number | R000004983 |
Scientific Title | Evaluation of guideline for primary hyperaldosteronism in Japan-2 Study |
Date of disclosure of the study information | 2010/09/03 |
Last modified on | 2016/03/02 15:50:01 |
Evaluation of guideline for primary hyperaldosteronism in
Japan-2 Study
PHAS-J2
Evaluation of guideline for primary hyperaldosteronism in
Japan-2 Study
PHAS-J2
Japan |
Primary aldosteronism
Medicine in general | Cardiology | Endocrinology and Metabolism |
Nephrology | Neurology | Endocrine surgery |
Urology |
Others
NO
Adherence of clinical guideline and establishment of standard medication of primary adlosteronism
Bio-equivalence
Confirmatory
Pragmatic
Phase IV
1)Adherance of clinical guideline
2)Establishment of standard medication
1)Implementation rate of each diagnostic procedure
2)Successful rate of the localization
3) Comparison of the effects of treatments with aldosterone antagonist and those with conventional antihypertensive agents
4) Comparison of the effects of medical treatments and surgical treatment
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
YES
Institution is considered as adjustment factor in dynamic allocation.
NO
Central registration
2
Treatment
Medicine |
Conventional antihypertensive agents with aldosterone antagonist
Conventional antihypertensive agents
20 | years-old | <= |
80 | years-old | >= |
Male and Female
Hypertensive patients in the outpatient clinics and hospitals, who full-fill the following 1) or 2) criteria:
1)treated hypertensive patients
2)untreated hypertensive patients with systolic blood pressure higher than 140mmHg or diastolic blood pressure higher than 90mmHg according to the guideline of the Japan Society of Hypertension
1)pregnant patients
2)patients taking aldosterone antagonist within the last one month
3)patients taking beta blocker or diuretics if not feasible to change to Ca antagonist or alfa antagonist
3)patients with the following diseases:
(1)secondary hypertension (renal hypertension,renovascular hypertension, primary aldosteronism, Cushing's syndrome, pheochromocytoma, etc)
(2)patients whom the attending doctors decides not suitable for the entry because of the unstable stage of the following complications: coronary diseases, arrhythmia, severe valvular diseases, cerebrovascular diseases, acute and chronic renal failure (serum Cr higher than 3mg/dl), acute and chronic liver diseases
4) Patients whom the attending doctor decides not suitable for the entry of the study.
1000
1st name | |
Middle name | |
Last name | Mitsuhide Naruse |
National Hospital Organization, Kyoto Medical Center
Department of Endocrinology, Clinical Research Institute for Endocrine and Metabolic Diseases
1-1 Fukakusa-Mukaihatacho, Fushimiku, Kyoto, 612-8555, Japan
075-641-9161
1st name | |
Middle name | |
Last name | Mitsuhide Naruse |
National Hospital Organization, Kyoto Medical Center
Department of Endocrinology, Clinical Research Institute for Endocrine and Metabolic Diseases
1-1 Fukakusa-Mukaihatacho, Fushimiku, Kyoto 612-8555, Japan
075-641-9161(6134)
mnaruse@kyotolan.hosp.go.jp
National Hospital Organization
National Hospital Organization
Japan
The Japan Endocrine Society
non
NO
NHO函館病院(北海道)、NHO仙台医療センター(宮城県)、NHO西群馬病院(群馬県)、NHO高崎総合医療センター(群馬県)、NHO宇都宮病院(栃木県)、NHO水戸医療センター(茨城県)、NHO千葉東病院(千葉県)、NHO埼玉病院(埼玉県)、NHO金沢医療センター(石川県)、NHO名古屋医療センター(愛知県)、NHO三重病院(三重県)、NHO三重中央医療センター(三重県)、NHO京都医療センター(京都府)、NHO大阪医療センター(大阪府)、NHO大阪南医療センター(大阪府)、NHO神戸医療センター(兵庫県)、NHO岡山医療センター(岡山県)、NHO呉医療センター・中国がんセンター(広島県)、NHO関門医療センター(山口県)、NHO小倉医療センター(福岡県)、NHO九州医療センター(福岡県)、NHO長崎医療センター(長崎県)、NHO長崎川棚医療センター(長崎県)、NHO熊本医療センター(熊本県)、五島中央病院(長崎県)、みさと健和病院(埼玉県)
2010 | Year | 09 | Month | 03 | Day |
Unpublished
Completed
2010 | Year | 06 | Month | 09 | Day |
2013 | Year | 03 | Month | 31 | Day |
2013 | Year | 03 | Month | 31 | Day |
2013 | Year | 03 | Month | 31 | Day |
2010 | Year | 09 | Month | 02 | Day |
2016 | Year | 03 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004983
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