Unique ID issued by UMIN | UMIN000004153 |
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Receipt number | R000004985 |
Scientific Title | A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria |
Date of disclosure of the study information | 2010/09/10 |
Last modified on | 2012/03/05 16:43:45 |
A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria
A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria
A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria
A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria
Japan |
Nocturia due to nocturnal polyuria
Urology |
Others
NO
To compare the efficacy and the safety of furosemide and gosha-jinki-gan for nocturia due to nocturnal polyuria
Safety,Efficacy
nocturnal urinary frequency and nocturnal polyuria index
safety, quality of life, serum BNP level, blood pressure, body fluid compartments
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Medicine |
furosemide, peroral administration, 20mg after lunch, once per day
gosha-jinki-gan, peroral administration, 7.5g/day, 3 times/day
50 | years-old | <= |
Not applicable |
Male and Female
1) 2 or more of I-PSS nocturia score
2) 35% or more of nocturnal polyuria index
3) 50 or more of age
4) systolic blood pressure 140mmHg or more, or diastolic blood pressure 90mmHg or more, or under treatment of hypertension
5) 20pg/ml or more and less than 200 pg/ml of serum BNP level
1) obvious neurogenic bladder
2) severe hypertension
3) severe complications
40
1st name | |
Middle name | |
Last name | Koji Yoshimura |
Kyoto University Graduate School of Medicine
Urology
54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto
1st name | |
Middle name | |
Last name | Koji Yoshimura |
Kyoto University Graduate School of Medicine
Urology
ky7527@kuhp.kyoto-u.ac.jp
Department of Urology, Kyoto University Graduate School of Medicine
none
Self funding
NO
2010 | Year | 09 | Month | 10 | Day |
Published
http://www.wiley.com/bw/journal.asp?ref=1757-5664&site=1
Both furosemide and GJG significantly improved the nocturia score in the I-PSS, the I-PSS QOL score, actual nocturnal frequency and hours of undisturbed sleep compared with those at baseline. Nocturnal frequency and nocturnal urine volume were more significantly reduced by furosemide treatment than with GJG treatment. The I-PSS total score and nocturnal urine volume significantly improved only by furosemide treatment.
Completed
2006 | Year | 09 | Month | 15 | Day |
2006 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 09 | Month | 02 | Day |
2012 | Year | 03 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000004985
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