Unique ID issued by UMIN | UMIN000004167 |
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Receipt number | R000005001 |
Scientific Title | Efficacy of aprepitant on postoperative nausea and vomiting: Assesement with patient-controlled prevention of nause and vomiting (PCPNV). |
Date of disclosure of the study information | 2010/09/07 |
Last modified on | 2013/03/21 09:57:51 |
Efficacy of aprepitant on postoperative nausea and vomiting: Assesement with patient-controlled prevention of nause and vomiting (PCPNV).
Aprepitant inhibits PONV
Efficacy of aprepitant on postoperative nausea and vomiting: Assesement with patient-controlled prevention of nause and vomiting (PCPNV).
Aprepitant inhibits PONV
Japan |
Patients undergoing dento-oral surgery
Anesthesiology | Operative medicine | Dental medicine |
Others
NO
To examine the efficacy of NK-1 receptor antagonist on PONV
Efficacy
Consumption of postoperative anti-emetic agent
Interventional
Parallel
Randomized
Individual
Single blind -investigator(s) and assessor(s) are blinded
Active
YES
YES
Institution is considered as a block.
YES
Numbered container method
2
Treatment
Medicine |
Aprepitant 125 mg was preoperatively administered in 20 patients undergoing oro-dental-surgeries and postoperative neusea and vomiting is evaluated.
Metoclopramide 10 mg was administered just before completion fo surgery in 20 patients undergoing oro-dental-surgeries and postoperative neusea a vomiting is evaluated. Preoperative administration of metoclopramide
18 | years-old | <= |
40 | years-old | > |
Male and Female
Patients for surgical correction of bite
Patients with pregnancy, having vomiting with 24 h before surgery in any etiology, allergy to any medications to be used prtioperatively, hepatic and renal disfunction.
Patients taking medications known to induce or inhibit cytochrome P-450 3A4.
40
1st name | |
Middle name | |
Last name | Eiji Masaki |
Tohoku University Graduate School of Dentistry
Division of Dento-oral Anesthesiology
4-1 Seiryou-machi, Aoba-ku, Sendai, Miyagi
022-717-8401
1st name | |
Middle name | |
Last name | Syomu |
Tohoku University Graduate School of Dentistry
Syomu
den-syomu@bereau.tohoku.ac.jp
Tohoku University Graduate School of Dentistry
Tohoku University Graduate School of Dentistry
Other
NO
2010 | Year | 09 | Month | 07 | Day |
Unpublished
Terminated
2010 | Year | 09 | Month | 01 | Day |
2010 | Year | 10 | Month | 01 | Day |
2010 | Year | 09 | Month | 07 | Day |
2013 | Year | 03 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005001
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