Unique ID issued by UMIN | UMIN000004279 |
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Receipt number | R000005130 |
Scientific Title | Antimicrobial Susceptibility in Identified Microbes Among Hospitalized Patients with Pneumonia (Additional Study of CJLSG 0911) |
Date of disclosure of the study information | 2010/09/28 |
Last modified on | 2021/10/26 09:08:04 |
Antimicrobial Susceptibility in Identified Microbes Among Hospitalized Patients with Pneumonia (Additional Study of CJLSG 0911)
Antimicrobial Susceptibility in Identified Microbes Among Hospitalized Patients with Pneumonia
Antimicrobial Susceptibility in Identified Microbes Among Hospitalized Patients with Pneumonia (Additional Study of CJLSG 0911)
Antimicrobial Susceptibility in Identified Microbes Among Hospitalized Patients with Pneumonia
Japan |
Community-acquired pneumonia (CAP), health-care-associated pneumonia (HCAP), hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP)pneumonia (VAP)
Pneumology | Infectious disease |
Others
NO
- To propose the appropriate initial antibiotic empirical treatment for patients with CAP, HCAP, HAP, and VAP, by investigating antimicrobial susceptibility in identified microbes among those patients.
- To investigate mechanisms for drug resistance in identified microbes.
- To propose the appropriate infection control practice, by molecular epidemiological analyses of identified microbes.
Others
Antimicrobial susceptibilities, mechanisms for drug resistance, and differences in molecular epidemiological findings, etc. in identified microbes among patients with CAP, HCAP, HAP, and VAP.
Exploratory
Explanatory
Not applicable
1) Antimicrobial susceptibilities in identified microbes.
2) The frequency of each identified microbe and those proportion of drug resistance in patients with CAP, HCAP, HAP, and VAP.
3) Mechanisms for drug resistance in identified microbes in patients with CAP, HCAP, HAP, and VAP.
4) Differences in molecular epidemiological findings in identified microbes among patients with CAP, HCAP, HAP, and VAP.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
The presence of a new infiltrate on a chest X-ray, or a computed tomography scan, plus at least 2 of the following criteria: 1) cough or purulent sputum, 2) pleuritic chest pain, 3) dyspnea, 4) fever or hypothermia (temperature >= 38 degrees or < 35 degrees), 5) white blood cell count >= 10,000 /mm3 or < 4,000 /mm3, and 6) hypoxemia (SpO2 < 90% or PaO2 < 60 Torr) or decline in oxygenation.
1) Patients who do not receive initial empirical antibiotic treatment.
2) Patients with obstructive pneumonia.
3) Pneumonia occurred in other hospitals and patients who were transferred from their hospitals with a tendency to improve.
4) Patients whose pneumonia recurred within 3 days after the last day of antibiotic treatment of a preceding pneumonia episode.
5) Patients who receive the treatment in an outpatient clinic.
6) Patients who are less than 20 years old.
1200
1st name | Yuichiro |
Middle name | |
Last name | Shindo |
Nagoya University Hospital
Respiratory Medicine
466-8550
65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
052-744-2167
yshindo@med.nagoya-u.ac.jp
1st name | Yuichiro |
Middle name | |
Last name | Shindo |
Nagoya University Hospital
Respiratory Medicine
466-8550
65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan
052-744-2167
yshindo@med.nagoya-u.ac.jp
Central Japan Lung Study Group
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine
Self funding
Department of Infectious Diseases, Nagoya University Hospital
Central Japan Lung Study Group
Nagoya University Hospital, Institutional Review Board
65 Tsurumai-cho, showa-ku, Nagoya 466-8550, Japan
052-744-2500
ethics@med.nagoya-u.ac.jp
NO
名古屋大学医学部附属病院(愛知県)
JA愛知厚生連豊田厚生病院(愛知県)
トヨタ記念病院(愛知県)
大垣市民病院(岐阜県)
公立陶生病院(愛知県)
国立病院機構名古屋医療センター(愛知県)
名古屋掖済会病院(愛知県)
豊橋市民病院(愛知県)
名古屋第一赤十字病院(愛知県)
名古屋第二赤十字病院(愛知県)
2010 | Year | 09 | Month | 28 | Day |
http://www.cjlsg.jp/activity.html
Published
https://journals.asm.org/doi/10.1128/JCM.03067-14?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rf
120
Results of this study have been partially published:
- http://www.ncbi.nlm.nih.gov/pubmed/25568434
- https://journals.asm.org/doi/10.1128/JCM.03067-14?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
2021 | Year | 10 | Month | 26 | Day |
2015 | Year | 02 | Month | 19 | Day |
Nosocomial pneumonia (hospital-acquired pneumonia and ventilator-associated pneumonia), neoplastic disease, immunosuppression, systolic blood pressure (SBP) <90 mmHg, respiratory rate (RR) >=30/min, and albumin <3.0 mg/dl (hypoalbuminemia) were more frequent in patients with bacteremia than in those without bacteremia. The SOFA score was higher in patients with bacteremia than in those without.
One hundred and two patients from the previous cohort study (18) and 18 patients from Nagoya University Hospital made a total of 120 patients with pneumonia due to K. pneumoniae included in the present study. Among them, 23 (19.2%) were classified as bacteremia, and 97 (80.8%) were classified as non-bacteremia.
None
Bacteremia due to K. pneumoniae
Completed
2010 | Year | 05 | Month | 07 | Day |
2010 | Year | 06 | Month | 24 | Day |
2010 | Year | 08 | Month | 01 | Day |
2011 | Year | 05 | Month | 01 | Day |
2013 | Year | 03 | Month | 01 | Day |
2014 | Year | 03 | Month | 01 | Day |
2014 | Year | 03 | Month | 01 | Day |
- This is an additional study of CJLSG 0911, entitled "Epidemiological Study for Hospitalized Patients with Community-acquired, Health-care-associated, Hospital-acquired, and Ventilator-associated Pneumonia in Japan: a Prospective Multicenter Follow-up Study" (UMIN000003306).
- Microbes, used in this study, are those which are identified in patients who have been enrolled in the CJLSG 0911 study.
- The start date of enrollment is the date that the collection of microbes was started.
2010 | Year | 09 | Month | 28 | Day |
2021 | Year | 10 | Month | 26 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005130
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