Unique ID issued by UMIN | UMIN000004390 |
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Receipt number | R000005241 |
Scientific Title | The impact of dipeptidyl peptidase-4 inhibitor on coronary microvascular function in patients with type2 diabetes mellitus |
Date of disclosure of the study information | 2010/11/01 |
Last modified on | 2015/04/27 11:50:14 |
The impact of dipeptidyl peptidase-4 inhibitor on coronary microvascular function in patients with type2 diabetes mellitus
The impact of dipeptidyl peptidase-4 inhibitor on coronary microvascular function in patients with type2 diabetes mellitus
The impact of dipeptidyl peptidase-4 inhibitor on coronary microvascular function in patients with type2 diabetes mellitus
The impact of dipeptidyl peptidase-4 inhibitor on coronary microvascular function in patients with type2 diabetes mellitus
Japan |
Type 2 diabetic patients with stable angina pectoris who undergo percutaneous coronary intervention
Cardiology |
Others
NO
To evaluate the effect of dipeptidyl peptidase-4 inhibitor on microvascular function with intracoronary pressure/temperature sensor-tipped guide wire
Efficacy
Exploratory
Change in index of microcirculatory index
Absolute and percent changes of high-sensitive CRP and adiponectine
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
No treatment
YES
YES
Institution is not considered as adjustment factor.
Central registration
2
Treatment
Medicine |
DPP-4 inhibitor tretment 1 year after measurement of baseline IMR value
no treatment
20 | years-old | <= |
85 | years-old | > |
Male and Female
1) Stable angina pectoris
2) Type2 diabetes mellitus who are controlled well
3) Culprit lesion involving 75% or more of the stenosis without LAD
4) Successful revascularization of target lesion
5) Patients providing written consent for participattion in this clinical trial on their own volition after receiving a thorough explanation of the study
1) Target lesion is left main coronary artery
2) Patients on hemodialysis
3) Patients with acute coronary syndorome
4) Patients with contraindication of antiplatelet or anticoagulation drug
5) Patients who are uncontrolled diabetes mellitus
6) Patients who are judged by the principal investigator to be ineligible for enrollment in the study
40
1st name | |
Middle name | |
Last name | Tohru Masuyama |
Hyogo College of Medicine
Cardiovascular Division
1-1 Mukogawa-cho, Nishinomiya-city, Hyogo 6638501 JAPAN
0798-45-6553
1st name | |
Middle name | |
Last name | Masashi Fukunaga |
Hyogo College of Medicine
Cardiovascular Division
1-1 Mukogawa-cho, Nishinomiya-city, Hyogo 6638501 JAPAN
0798-45-6553
Cardiovascular Division, Hyogo College of Medicine
None
Self funding
NO
兵庫医科大学病院(兵庫県)
2010 | Year | 11 | Month | 01 | Day |
Unpublished
Completed
2010 | Year | 09 | Month | 01 | Day |
2010 | Year | 11 | Month | 01 | Day |
2010 | Year | 10 | Month | 14 | Day |
2015 | Year | 04 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005241
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