Unique ID issued by UMIN | UMIN000004973 |
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Receipt number | R000005433 |
Scientific Title | Evaluation of the effects of ultra-long acting insulin analogue on diabetic vascular complication |
Date of disclosure of the study information | 2011/03/30 |
Last modified on | 2016/08/10 17:09:37 |
Evaluation of the effects of ultra-long acting insulin analogue on diabetic vascular complication
EVOLUTION
Evaluation of the effects of ultra-long acting insulin analogue on diabetic vascular complication
EVOLUTION
Japan |
Type2 diabetes
Endocrinology and Metabolism |
Others
NO
To clarify the effects of detemir or glargin treatment on atherosclerotic markers.
Others
To clarify the effects of detemir or glargin treatment on atherosclerotic markers.
Exploratory
Pragmatic
Not applicable
Flow mediated vasodilatation
urinary albumin excretion, Vascular endothelial growth factor, Plasminogen activator inhibitor-1, , Adiponectin, Leptin, Ghrelin, high sensitive CRP
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Medicine |
First, detemir treatment for 6 months, and then glargin treatment for 6 months
First, glargin treatment for 6 months, and then detemir treatment for 6 months
20 | years-old | <= |
75 | years-old | >= |
Male and Female
type 2 diabetic patients whose HbA1c level over 7%
Patients modified ACEI/ARB, statin, pioglitzone therapy within 1 months
Patients with pregnancy
60
1st name | |
Middle name | |
Last name | Yoshihiro Miyamoto |
National Cerebral Cardiovascular Center
Endocrinology and Metabolism
5-7-1 Fujishiro-dai, Suita, Osaka, Japan
1st name | |
Middle name | |
Last name | Hisashi Makino |
National Cerebral Cardiovascular Center
Endocrinology and Metabolism
EVOLUTION study group
Japan Cardiovascular Research Foundation
Non profit foundation
NO
2011 | Year | 03 | Month | 30 | Day |
Published
Completed
2009 | Year | 12 | Month | 01 | Day |
2010 | Year | 02 | Month | 01 | Day |
2011 | Year | 01 | Month | 28 | Day |
2016 | Year | 08 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005433
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