Unique ID issued by UMIN | UMIN000004606 |
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Receipt number | R000005500 |
Scientific Title | How to assess the individual sensitivity to intravenous anesthetic |
Date of disclosure of the study information | 2010/11/23 |
Last modified on | 2016/12/29 15:55:28 |
How to assess the individual sensitivity to intravenous anesthetic
How to assess the individual sensitivity to intravenous anesthetic
How to assess the individual sensitivity to intravenous anesthetic
How to assess the individual sensitivity to intravenous anesthetic
Japan |
Breast cancer
Anesthesiology |
Malignancy
NO
As sensitivity to intravenous anesthetic is widely varied among patients, EEG monitor is used. The purpose of this study is to fine the method to assess the sensitivity to intravenous anesthetic without using EEG monitor by investigating the relationship between estimated effect-site concentration (Ce) of anesthetic at loss of response to verbal command and Ce at some status assessed by EEG monitor. We also explore new evaluating method of anesthetic effect on EEG.
PK,PD
Exploratory
To obtain the relationship between the effect-site concentration and that required for maintenance of anesthesia.
To find a new method to evaluate the effect of anesthetic by investigating the concentration related changes of EEG.
Observational
20 | years-old | <= |
70 | years-old | > |
Female
Patients of ASA-PS I or II, who are scheduled mammectomy for their breast cancer
patients who has a disease in central nervous system. patients who are using the drugs that may influence the EEG, such as psychomimetic drugs
30
1st name | |
Middle name | |
Last name | Satoshi Hagihira |
Osaka University Graduate School of Medicine
Department of Anesthesiology and Intensive Care Medicine
2-2 Yamadaoka, Suita City, Osaka
1st name | |
Middle name | |
Last name | Satoshi Hagihira |
Osaka University Graduate School of Medicine
Department of Anesthesiology and Intensive Care Medicine
2-2 Yamadaoka, Suita City, Osaka
Osaka University Graduate School of Medicine
Departmential sources
Self funding
NO
大阪大学医学部附属病院(大阪府)
2010 | Year | 11 | Month | 23 | Day |
Unpublished
Completed
2009 | Year | 02 | Month | 18 | Day |
2009 | Year | 07 | Month | 01 | Day |
2010 | Year | 10 | Month | 31 | Day |
2010 | Year | 10 | Month | 31 | Day |
Three effect-site concentrations in each patient are recorded; at loss of response, maintenance of anesthesia, recovery of response.
2010 | Year | 11 | Month | 23 | Day |
2016 | Year | 12 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005500
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