Unique ID issued by UMIN | UMIN000004774 |
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Receipt number | R000005685 |
Scientific Title | Individual difference of folate metabolism caused by genetic polymorphisms and its improvement by a folate-fortified food (folic acid fortified bread). |
Date of disclosure of the study information | 2011/05/31 |
Last modified on | 2010/12/22 10:52:08 |
Individual difference of folate metabolism caused by genetic polymorphisms and its improvement by a folate-fortified food (folic acid fortified bread).
Improvement of mutants of folate metabolism by folic acid-fortified bread.
Individual difference of folate metabolism caused by genetic polymorphisms and its improvement by a folate-fortified food (folic acid fortified bread).
Improvement of mutants of folate metabolism by folic acid-fortified bread.
Japan |
depressive state
Medicine in general | Neurology | Psychiatry |
Adult |
Others
YES
Reduction of depression score of individuals with depression-susceptible genetic polymorphism by folic acid supplementation.
Safety,Efficacy
Confirmatory
Pragmatic
Not applicable
serum folate, serum homocysteine and CES-D depression score.
Intake of all nutrients, general blood biochemistry
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Prevention
Gene | Food | Behavior,custom |
folic acid-fortified bread intake group
control bread intake group
19 | years-old | <= |
22 | years-old | >= |
Female
healthy Japanese women
patients, supplement taker, drug taker.
50
1st name | |
Middle name | |
Last name | Yasuo Kagawa |
Kagawa Nutrition University
Faculty of Nutrition
3-9-21 Chiyoda, Sakado city, Saitama, Japan 350-0288
049-282-3618
1st name | |
Middle name | |
Last name | Yasuo Kagawa |
Kagawa Nutrition University
Faculty of Nutrition
3-9-21 Chiyoda, Sakado City, Saitama Japan 350-0288
049-282-3618
kagawa@eiyo.ac.jp
Kagawa Nutrition University
Kagawa Nutrition University
Self funding
NO
女子栄養大学
2011 | Year | 05 | Month | 31 | Day |
Unpublished
Supplementation of folic acid was effective in reducing depression scores in Japanese women with depression-related polymorphisms.
Completed
2009 | Year | 08 | Month | 31 | Day |
2009 | Year | 10 | Month | 01 | Day |
2010 | Year | 12 | Month | 22 | Day |
2010 | Year | 12 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005685
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