Unique ID issued by UMIN | UMIN000004786 |
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Receipt number | R000005697 |
Scientific Title | PET microdose study of donepezi in humans |
Date of disclosure of the study information | 2010/12/24 |
Last modified on | 2010/12/24 14:14:45 |
PET microdose study of donepezi in humans
Donepezil PET
PET microdose study of donepezi in humans
Donepezil PET
Japan |
normal volunteer
Adult |
Others
NO
to elucidate pharmacokinetics of donepezil in normal volunteers
Pharmacokinetics
Confirmatory
Explanatory
Not applicable
radioactivity of donpezil in the brain
sequential changes in donepezil radioactivity in the brain by 60minafter administration
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Dose comparison
NO
NO
Institution is not considered as adjustment factor.
YES
Numbered container method
2
Treatment
Medicine |
To analyze pharmacokinetics of C-11 donepezil after 1mg (n=6) oral administration. The study period is from January to March 2022.
To analyze pharmacokinetics of C-11 donepezil after 3mg (n=6) oral administration. The study period is from January to March 2022.
40 | years-old | <= |
65 | years-old | >= |
Male and Female
normal volunteer
liver dysfunction, ECG abnormality, past history of gastric ulcer, symptoms of extrapyramidal systems, intake of other drugs, pregnant,
12
1st name | |
Middle name | |
Last name | Jun Hatazawa |
Osaka University Hospital
Nuclear Medicine
2-2 Yamadaoka Suita, Osaka
81-6-6879-3461
1st name | |
Middle name | |
Last name | Jun Hatazawa |
Osaka University Hospital
Nuclear Medicine
2-2 Yamadaoka Suita, Osaka
81-6-6879-3461
http://www.tracer.med.osaka-u.ac.jp/index-jp.htm
hatazawa@tracer.med.osaka-u.ac.jp
Department of Nuclear Medicine, Osaka University Hospital
New Energy and Industrial Technology Development Organization Japan
Japan
NO
大阪大学医学部附属病院(大阪府)
2010 | Year | 12 | Month | 24 | Day |
Unpublished
Open public recruiting
2010 | Year | 12 | Month | 24 | Day |
2010 | Year | 12 | Month | 01 | Day |
2010 | Year | 12 | Month | 24 | Day |
2010 | Year | 12 | Month | 24 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000005697
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