Unique ID issued by UMIN | UMIN000005064 |
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Receipt number | R000006023 |
Scientific Title | Comparison of effects of azelnidipine and trichlormethiazide in combination with olmesartan on blood pressure and metabolic parameters in hypertensive type 2 diabetic patients |
Date of disclosure of the study information | 2011/02/11 |
Last modified on | 2011/02/10 08:51:40 |
Comparison of effects of azelnidipine and trichlormethiazide in combination with olmesartan on blood pressure and metabolic parameters in hypertensive type 2 diabetic patients
Comparison of CCB and thiazide diuretics
Comparison of effects of azelnidipine and trichlormethiazide in combination with olmesartan on blood pressure and metabolic parameters in hypertensive type 2 diabetic patients
Comparison of CCB and thiazide diuretics
Japan |
type 2 diabetic patients with hypertension
Endocrinology and Metabolism |
Others
NO
The aim of this study is to compare the effects of combination treatment of ARB (olmesartan, 20 mg/day) with a calcium channel blocker (CCB) or with a low-dose thiazide diuretic on blood pressure (BP) and various metabolic parameters in hypertensive patients with type 2 diabetes
Efficacy
Exploratory
Pragmatic
Not applicable
Comparison of the effects on blood pressure (BP) and various metabolic parameters.
Interventional
Cross-over
Randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
azelnidipine (16 mg/day)
trichlormethiazide (1 mg/day)
Not applicable |
Not applicable |
Male and Female
The inclusion criteria were patients with type 2 diabetes mellitus and hypertension in whom the target clinic blood pressure (<130/80 mmHg) could not be achieved despite treatment with olmesartan 20 mg once daily
Patients with HbA1c higher than 8.4% were excluded from the study. In addition, patients with severe renal or hepatic disease, overt cardiovascular disease, and malignancy were excluded
50
1st name | |
Middle name | |
Last name | Tomoya Mita |
Juntendo University Graduate School of Medicine
Department of Medicine, Metabolism and Endocrinology
2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan
1st name | |
Middle name | |
Last name |
Juntendo University Graduate School of Medicine
Metabolism and Endocrinology
03-3813-3111
Juntendo University Graduate School of Medicine
Juntendo University Graduate School of Medicine
Self funding
NO
2011 | Year | 02 | Month | 11 | Day |
Partially published
Completed
2007 | Year | 11 | Month | 15 | Day |
2008 | Year | 01 | Month | 01 | Day |
2010 | Year | 10 | Month | 01 | Day |
2011 | Year | 02 | Month | 10 | Day |
2011 | Year | 02 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006023
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