Unique ID issued by UMIN | UMIN000005518 |
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Receipt number | R000006145 |
Scientific Title | ARB+diurites vs ARB+Ca blocker |
Date of disclosure of the study information | 2011/04/27 |
Last modified on | 2015/05/28 15:30:00 |
ARB+diurites vs ARB+Ca blocker
TAT Kobe
ARB+diurites vs ARB+Ca blocker
TAT Kobe
Japan |
hypertension
Cardiology |
Others
NO
to compare the effectiveness of ARB/Ca-blocker and ARB/diuretis
Efficacy
Confirmatory
Pragmatic
Not applicable
blood pressure after 12 weeks
laboratory data:WBC,RBC,Hb,Hct,Plt,LDL-C,TG,HDL-C,AST,ALT,LDH,ALP,ganma-GTP,CK,FBS,IRI,Alb,BUN,Cr,UA,Na,K,Cl,PRA,aldsterone,U-Na,U-Cl,U-Cr,U-ALb,hs-CRP,HbA1c
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Uncontrolled
NO
NO
Institution is not considered as adjustment factor.
NO
Numbered container method
2
Treatment
Medicine |
telmisaltan:40mg + HCTZ:12.5mg
telmisaltan:40mg + amlodipine:12.5mg
65 | years-old | <= |
Not applicable |
Male and Female
hypertension patients who do not reach the target blood pressure with ARB only.
1) uncontorable hypertension(DBP>110)
2) secondary hepertension
3) diabetes mellitus patient who are uncontorable(HbA1c>8.0%) or use insulin
4) stroke or myocardial infarction or severe cardiovascular disease within past 3 months
5) severe liver dysfunction
6) severe renal failure(Cr>2.0)
7) malignant disease
8) pregnancy woman
9) patient who can not secrete bille enoughly
10) hypersensivity for telmisaltan or HCTZ
11) hypersensivity for Tiazido type medicine
12) hypersensivity for Ca-blocker
13) patient who are judged inappropriate condition for study by doctor
60
1st name | |
Middle name | |
Last name | Tatsuro Ishida |
Kobe University Hospital
Cardiology
7-5-1 Kusunoki-cho, Chuo-ku, Kobe
078-382-5846
ishida@med.kobe-u.ac.jp
1st name | |
Middle name | |
Last name | Tatsuro Ishida |
Kobe University Hospital
Cardiology
7-5-1 Kusunoki-cho, Chuo-ku, Kobe
078-382-5846
ishida@med.kobe-u.ac.jp
Kobe University Hospital,Division of Cardiology
None
Self funding
NO
神戸大学医学部附属病院(兵庫県)
2011 | Year | 04 | Month | 27 | Day |
Published
Main results already published
2010 | Year | 10 | Month | 01 | Day |
2010 | Year | 10 | Month | 01 | Day |
2011 | Year | 04 | Month | 27 | Day |
2015 | Year | 05 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006145
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