Unique ID issued by UMIN | UMIN000005238 |
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Receipt number | R000006228 |
Scientific Title | The effect of Sitagliptin on Coronary Flow Reserve in Type 2 Diabetic Patients with Coronary Artery Disease |
Date of disclosure of the study information | 2011/03/11 |
Last modified on | 2024/03/21 12:59:00 |
The effect of Sitagliptin on Coronary Flow Reserve in Type 2 Diabetic Patients with Coronary Artery Disease
The effect of Sitagliptin on Coronary Flow Reserve
The effect of Sitagliptin on Coronary Flow Reserve in Type 2 Diabetic Patients with Coronary Artery Disease
The effect of Sitagliptin on Coronary Flow Reserve
Japan |
Type 2 Diabetic Patients with Coronary Artery Disease
Cardiology | Endocrinology and Metabolism |
Others
NO
To investigate the effect of the DPP-4 Inhibitor "Sitagliptin" on coronary flow reserve in type 2 diabetic patients with coronary artery disease
Safety,Efficacy
Exploratory
Pragmatic
Not applicable
Coronary flow reserve by coronary flow wire
1,5-AG, CAVI, FMD, MMP-9, PTX3
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Add-on Stagliptin
20 | years-old | <= |
80 | years-old | > |
Male and Female
1)Type2 diabetic patients with coronary artery disease.(HbA1c >=6.5% JDS)
2)Age >=20 years, <80 years (Male and Female)
3)A consent form for participating in this study is submitted
1)Patients with type 1 diabetes
2)Patients receiving Alfa-glycosidase inhibitor, Insulin or Glinide
3)History of severe ketosis, diabetic coma or precoma within 6 months
4)Patients with severe infections, before or after operation, or with serious trauma
5)Patients who are pregnant, breastfeeding or intention to becoming pregnant
6)Patients with exceeding the moderate renal impairment
7)Having allergy to DPP-4 Inhibitor
8)Patients with significant stenosis at major 3 coronary artery or with history for PCI
9)Other patients determined to be inappropriate by physician
20
1st name | Hiroyasu |
Middle name | |
Last name | Uzui |
University of Fukui, Faculty of Medical Sciences
Division of cardiovascular Medicine
9101193
23-3 Shimoaizuki, Eiheiji-cho, Fukui 910-1193, Japan.
0776-61-3111
huzui@u-fukui.ac.jp
1st name | Hiroyasu |
Middle name | |
Last name | Uzui |
University of Fukui, Faculty of Medical Sciences
Division of cardiovascular Medicine
9101193
23-3 Shimoaizuki, Eiheiji-cho, Fukui 910-1193, Japan.
0776-61-3111
huzui@u-fukui.ac.jp
University of Fukui Faculty of Medical Sciences, Division of cardiovascular Medicine
None
Self funding
Japan
University of Fukui Medical Reseach Support Center
23-3 Shimoaizuki Matsuoka-cho Eiheiji Fukui Japan
0776-61-3111
chiken@ml.u-fukui.ac.jp
NO
福井大学医学部附属病院
2011 | Year | 03 | Month | 11 | Day |
none
Unpublished
none
24
Recruitment of participants
2024 | Year | 03 | Month | 21 | Day |
Recruitment of participants
Recruitment of participants
none
Recruitment of participants
Preinitiation
2011 | Year | 01 | Month | 18 | Day |
2011 | Year | 03 | Month | 01 | Day |
2013 | Year | 12 | Month | 01 | Day |
2014 | Year | 06 | Month | 01 | Day |
2014 | Year | 06 | Month | 01 | Day |
2014 | Year | 06 | Month | 01 | Day |
2011 | Year | 03 | Month | 11 | Day |
2024 | Year | 03 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006228
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