Unique ID issued by UMIN | UMIN000005323 |
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Receipt number | R000006327 |
Scientific Title | Diagnosis of Early LIver CAncer Through EOB-MRI Study |
Date of disclosure of the study information | 2011/03/28 |
Last modified on | 2011/03/27 13:20:19 |
Diagnosis of Early LIver CAncer
Through EOB-MRI Study
DELICATE Study
Diagnosis of Early LIver CAncer
Through EOB-MRI Study
DELICATE Study
Japan |
HCC borderline lesion
Hepato-biliary-pancreatic medicine | Radiology |
Malignancy
NO
The purpose of our study is to evaluate
a natural course of non-hypervascular HCCs and borderline leions by using EOB-MRI and other imaging modalities.
Efficacy
Exploratory
Not applicable
Evaluate a dediferential rate of non-hypervascular tumors in natural course
1.Evaluate a dedifential rate of each nodule wheter the result of the image of post-vascular phase of the tumor affect the dedifential rate.
2.Compare the hepatobiliary phase images of EOB-MRI with histological results of tumors.
3.Compare the hepatobiliary phase images of EOB-MRI with expression of transporters of tumors.
4.Compare the dediferention rate of tumors between HBV and HCV patients.
5.Histological evaluation of tumors that
can detect on ultrasonography with magnetic navigation system while EOB-MRI failed to detect.
6.Histological evaluation of tumors that
can detect on EOB-MRI while fundamental B-mode ultrasonography failed to detect.
We use ultrasonography with magnetic navigation system to acquire specimens.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1.20 Years and older.
2.Patient who have HCV, HBV and non-virus related chronic liver disease
without alcohol related choronic liver disease.
3.Nodules that diagnosed non-hyper vascular at least 2 imaging modalities.
4. Patiens who have non-hyper tumors and classical HCCs, but classical HCCs can be treated curatively.
5.Patient who have a treatment career of HCC once in the past, but received a curative treatment.
6.Patients who can receve a regular imaging examinations.
7.Written Informed Consent must be obtained.
8.ECOG Performance status of 0 or 1.
1.Known allergy to the investigational agent or any agent given in association with this trial.
2.Patiens who have severe liver damage.
3.Asthma patients
4.Patient who has metal in the body
5.patient having the active digestive organs bleeding.It is a case with the hospitalization career within the past one month.
6.A patient of the minority.
7.Pregnant or breast-feeding patients.
8.ECOG Performance status of more than 2.
9. Any condition that could jeopardize the safety of the patient or their compliance in the study
400
1st name | |
Middle name | |
Last name | Masatoshi Kudo |
Kinki University Faculty of Medicine
Department of Gastroenterology and Hepatology
377-2, Oono-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan
1st name | |
Middle name | |
Last name | Tatsuo Inoue |
Kinki University Faculty of Medicine
Department of Gastroenterology and Hepatology
377-2, Oono-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan
t-inoue@med.kindai.ac.jp
Japan Liver Oncology Group
Japan Liver Oncology Group
Other
Japan
NO
2011 | Year | 03 | Month | 28 | Day |
Unpublished
Open public recruiting
2011 | Year | 03 | Month | 02 | Day |
2011 | Year | 04 | Month | 01 | Day |
The purpose of this study is to evaluate
a dediferential rate of non-hypervascular
tumors prospectively by using imaging modalities.
2011 | Year | 03 | Month | 27 | Day |
2011 | Year | 03 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006327
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