Unique ID issued by UMIN | UMIN000005592 |
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Receipt number | R000006614 |
Scientific Title | Development of oral taurine therapy for the treatment of stroke-like epiodes of MELAS |
Date of disclosure of the study information | 2011/05/12 |
Last modified on | 2019/03/27 09:11:41 |
Development of oral taurine therapy for the treatment of stroke-like epiodes of MELAS
Taurine therapy for stroke-like epiodes of MELAS
Development of oral taurine therapy for the treatment of stroke-like epiodes of MELAS
Taurine therapy for stroke-like epiodes of MELAS
Japan |
MELAS
Neurology |
Others
YES
To evaluate the efficacy of taurine for the prevention of stroke-like episodes of MELAS
Efficacy
-Frequency of stroke-like episodes
-Score of neurological disability
-Degree of brain MRI lesions
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Twelve patients with MELAS having A3243G and T3271C mutations in the mitochondrial DNA are enrolled in the study. Oral taurine (12 g/d>BW40 kg; 9 g/d:25-39 kg; 6 g/d:15-24 kg; 3 g/d<15 kg) is administered to the patients for 24 months to evaluate the efficacy of the prevention for stroke-like episodes.
Not applicable |
Not applicable |
Male and Female
Male and female patients
none
10
1st name | |
Middle name | |
Last name | Yutaka Ohsawa |
Kawasaki Medical School
Neurology
577 Matsushima, Kurashiki-city, Okayama 701-0192, Japan
086-462-1111
yosawa@med.kawasaki-m.ac.jp
1st name | |
Middle name | |
Last name | Yutaka Ohsawa |
Kawasaki Medical School
Neurology
577 Matsushima,Kurashiki-city, Okayama 701-0192, Japan
086-462-1111
http://www.kawasaki-m.ac.jp/med/kenkyu/01.html
yosawa@med.kawasaki-m.ac.jp
Department of Neurology, Kawasaki Medical School
Department of Neurology, Kawasaki Medical School
Other
Japan
School of Medicine, Juntendo University
NO
川崎医科大学附属病院(岡山県)/Kawasaki Medical School Hospital
新潟大学医歯学総合病院(新潟県)/Niigata University Medical & Dental Hospital
名古屋第一赤十字病院(愛知県)/Japanese Red Cross Nagoya Daiichi Hospital
山形大学医学部附属病院(山形県)/Yamagata University Hospital
2011 | Year | 05 | Month | 12 | Day |
Unpublished
Completed
2011 | Year | 05 | Month | 09 | Day |
2011 | Year | 04 | Month | 11 | Day |
2011 | Year | 06 | Month | 01 | Day |
2019 | Year | 03 | Month | 31 | Day |
2011 | Year | 05 | Month | 12 | Day |
2019 | Year | 03 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006614
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