Unique ID issued by UMIN | UMIN000005836 |
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Receipt number | R000006896 |
Scientific Title | Phase I study of DCs therapy encoding mRNA derived from cancer antigens targeting advanced HCC & pancreatic cancer. |
Date of disclosure of the study information | 2011/06/26 |
Last modified on | 2012/04/10 16:31:23 |
Phase I study of DCs therapy encoding mRNA derived from cancer antigens targeting advanced HCC & pancreatic cancer.
Phase I study of DCs therapy encoding mRNA derived from cancer antigens targeting advanced HCC & pancreatic cancer.
Phase I study of DCs therapy encoding mRNA derived from cancer antigens targeting advanced HCC & pancreatic cancer.
Phase I study of DCs therapy encoding mRNA derived from cancer antigens targeting advanced HCC & pancreatic cancer.
Japan |
HCC , Pancreatic cancer
Hepato-biliary-pancreatic medicine | Hepato-biliary-pancreatic surgery |
Malignancy
NO
The purpose of this study is to evaluated the safety and toxicity of DCs therapy encoding mRNA derived from cancer antigens targeting advanced HCC & pancreatic cancer.
Safety
To evaluate the safety and to find out the recommended dose
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Vaccine |
dose escalation
20 | years-old | <= |
85 | years-old | >= |
Male and Female
1. Evaluable tumor lesion(s)
2. Predicted life expectancy of at least 3 months
3. Performance status 0-1 (ECOG)
4. No radiotherapy, chemotherapy or immunotherapy within 4 weeks prior to the study
5. Written informed consent
1. Adequate baseline organ functions
2. No history of serious allergic
12
1st name | |
Middle name | |
Last name | Masaaki Oka |
Yamaguchi University Graduate School of Medicine
Digestive surgery and surgical oncology
1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan
1st name | |
Middle name | |
Last name |
Yamaguchi University Graduate School of Medicine
Digestive surgery and surgical oncology
1-1-1 Minami-Kogushi, Ube, Yamaguchi, 755-8505, Japan
Yamaguchi University Graduate School of Medicine, Digestive surgery and surgical oncology
Yamaguchi University Graduate School of Medicine, Digestive surgery and surgical oncology
Self funding
NO
2011 | Year | 06 | Month | 26 | Day |
Partially published
Completed
2004 | Year | 04 | Month | 27 | Day |
2004 | Year | 05 | Month | 01 | Day |
2011 | Year | 06 | Month | 22 | Day |
2012 | Year | 04 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000006896
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