Unique ID issued by UMIN | UMIN000006080 |
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Receipt number | R000007194 |
Scientific Title | Uncontrol trial of targeted therapy on chronic glomerulonephritis |
Date of disclosure of the study information | 2011/08/01 |
Last modified on | 2011/07/29 22:56:03 |
Uncontrol trial of targeted therapy on chronic glomerulonephritis
Uncontrol trial of targeted therapy on chronic glomerulonephritis
Uncontrol trial of targeted therapy on chronic glomerulonephritis
Uncontrol trial of targeted therapy on chronic glomerulonephritis
Japan |
chronic glomerulonephritis
Nephrology |
Others
NO
To assess the effects and safety of targeted therapy on chronic blomerulonephritis
Safety,Efficacy
Confirmatory
Explanatory
Phase III
urinalysis, the cumulative dose of prednisolone and the cumulative dose of immunosuppressive drugs
the adverse effects of prednisolone, the adverse effects of immunosuppressive drugs, the adverse effects of targeted therapy
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Rituximab 375mg/2 once a week total 4 times, tocilizumab 8 mg/kg once a month total 3 times, or abatacept 500mg once a month total 7 times, 24 months follow-up
20 | years-old | <= |
Not applicable |
Male and Female
chronic glomerulonephritis on biopsy,
rebellant,
patients with participation after written informed concent
Patients with positive serology for hepatitis B, C or HIV,
severe renal dysfunction,
severe liver dysfunction,
pregnant woman
25
1st name | |
Middle name | |
Last name | Yoshiyuki Toya |
Yokohama City University Hospital
Department of Nephrology and Hypertension
Fukuura 3-9, Kanazawa-ku, Yokohama, Kanagawa
1st name | |
Middle name | |
Last name | Tatsuo Hashimoto |
Yokohama City University Hospital
Department of Nephrology and Hypertension
Fukuura 3-9, Kanazawa-ku, Yokohama, Kanagawa
Department of Cardiorenal Medicine, Yokohama City University School of Medicine
Yokohama City University Hospital
Self funding
NO
2011 | Year | 08 | Month | 01 | Day |
Unpublished
Open public recruiting
2011 | Year | 08 | Month | 01 | Day |
2011 | Year | 08 | Month | 01 | Day |
2011 | Year | 07 | Month | 29 | Day |
2011 | Year | 07 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007194
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