Unique ID issued by UMIN | UMIN000006243 |
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Receipt number | R000007388 |
Scientific Title | Phase II study of carboplatin/pemetrexed/bevacizumab for non-squamous NSCLC with carcinomatous pleuritis (NEJ013A) |
Date of disclosure of the study information | 2011/10/01 |
Last modified on | 2016/10/31 17:32:37 |
Phase II study of carboplatin/pemetrexed/bevacizumab for non-squamous NSCLC with carcinomatous pleuritis (NEJ013A)
Phase II of CBDCA/PEM/BEV for NSCLC with carcinomatous pleuritis
Phase II study of carboplatin/pemetrexed/bevacizumab for non-squamous NSCLC with carcinomatous pleuritis (NEJ013A)
Phase II of CBDCA/PEM/BEV for NSCLC with carcinomatous pleuritis
Japan |
Non-small cell lung cancer (non-squamous cell carcinoma)
Pneumology |
Malignancy
NO
To evaluate the safety and efficacy of CBDCA/PEM/BEV for NSCLC with carcinomatous pleuritis
Safety,Efficacy
The rate of controlled pleural effusion at 8 weeks
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
carboplatin/pemetrexed/bevacizumab
20 | years-old | <= |
Not applicable |
Male and Female
1. Pathologically confirmed NSCLC (non-squamous cell carcinoma)
2. Clinical stage IV or post-operative recurrence
3. Massive pleural effusion including malignant cells that requires tube drainage.
4. Chemotherapy naive except for EGFR-TKI
5. Aged over 20 years old with performance status 0-2
6. With addequate organ functions
7. With written informed consent
1. Clinically ineligible interstitial pneumonitis
2. Episode of hemoptysis
3. With brain metastasis, or tumor with large vessel invation or cavity formation
4. With active gastrointestinal ulcer
5. With severe comorbidities
6. With inadequate conditions judged by the attending physician
30
1st name | |
Middle name | |
Last name | Kazuhiro Usui |
Kanto Medical Center NTT-EC
Division of Respirology and Chest Surgery
5-9-2, Higashi-gotanda, Shinagawa-ku, Tokyo
03-3448-6111
usui@east.ntt.co.jp
1st name | |
Middle name | |
Last name | Kazuhiro Usui |
Kanto Medical Center NTT-EC
Division of Respirology and Chest Surgery
5-9-2, Higashi-gotanda, Shinagawa-ku, Tokyo
03-3448-6111
usui@east.ntt.co.jp
North-East Japan study group
North-East Japan study group
Self funding
NO
2011 | Year | 10 | Month | 01 | Day |
Unpublished
Completed
2011 | Year | 08 | Month | 29 | Day |
2011 | Year | 10 | Month | 01 | Day |
2011 | Year | 08 | Month | 29 | Day |
2016 | Year | 10 | Month | 31 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007388
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Research case data | |
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