Unique ID issued by UMIN | UMIN000006449 |
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Receipt number | R000007656 |
Scientific Title | A population-based study of Streptococcus suis infections in humans in Phayao Province in the northern Thailand |
Date of disclosure of the study information | 2011/10/01 |
Last modified on | 2011/10/01 17:21:50 |
A population-based study of Streptococcus suis infections in humans in Phayao Province in the northern Thailand
An epidemiological study of Streptococcus suis infections in Thailand
A population-based study of Streptococcus suis infections in humans in Phayao Province in the northern Thailand
An epidemiological study of Streptococcus suis infections in Thailand
Asia(except Japan) |
Streptococcus suis infection
Infectious disease |
Others
NO
To determine the incidence and the transmission mode of S. suis infection in the northern Thailand
Others
Clinical and microbiological study
Exploratory
Pragmatic
Not applicable
Detection of human case
Isolation of causative bacteria
Observational
Not applicable |
Not applicable |
Male and Female
After January 2010, the human case who is positive culture from the sterile sites such as blood or CSF and PCR for S. suis is positive at 7 hospitals in Phayao Provinces in the northern Thailand
None
300
1st name | |
Middle name | |
Last name | Kazunori Oishi |
Osaka University
Research Institute for Microbial Diseases
3-1 Yamadaoka, Suita, Osaka Prefecture
06-6879-4253
1st name | |
Middle name | |
Last name | Kazunori Oishi |
Osaka University
Research Institute for Microbial Diseases
3-1 Yamadaoka, Suita, Osaka Prefecture
06-6879-4253
oishik@biken.osaka-u.ac.jp
Osaka University
Ministry of Education, Science and Culture
Japan
Department of Medical Sciences, Ministry of Public Health
Department of Medical Sciences, Ministry of Public Health
NO
パヤオ病院、チェンカム病院
2011 | Year | 10 | Month | 01 | Day |
Unpublished
A prospective study of S. suis infections in humans was conducted in Phayao Province, in the northern Thailand to determine the incidence and the transmission mode of this disease in this region in 2010. Thirty-one cases with the case fatality rate of 15.6% were confirmed, and the estimated incidence in this year was 6.2 per 100000 in the general population in 2010. A peak incidence was found in May of 2010. The median age of patients were 53 and the male sex was 64.5%. Consumption of raw pork products was confirmed in 22 cases and the median incubation period (range) was 2 (0-11) days after consumption of raw pork products. Isolates from 31 cases were serotype 2 for 23 cases (74.2%) and serotype 14 for 8 cases (25.8%). The major sequence types (STs) found were ST1 (n=20) for serotypes 2 and ST105 (n=8) for serotype 14.
Open public recruiting
2009 | Year | 01 | Month | 11 | Day |
2010 | Year | 01 | Month | 01 | Day |
2010 | Year | 12 | Month | 01 | Day |
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2014 | Year | 12 | Month | 01 | Day |
The epidemiological analyses suggested three possible clusters including 16 cases. In the largest possible cluster including 10 cases in Chiang Khum and the neighboring districts during May, 2010, the source of infection in four cases was estimated as the raw pork dish served in a restaurant in this district. The microbiological analysis confirmed that 3 of 4 cases associated with consumption of raw pork dish at this restaurant were attributable to an identical strain of serotype 2 with ST1 and pulsotypes of A2.
2011 | Year | 10 | Month | 01 | Day |
2011 | Year | 10 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007656
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