Unique ID issued by UMIN | UMIN000006682 |
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Receipt number | R000007896 |
Scientific Title | Early prediction of survival to gefitinib or chemotherapy using integrated FDG-PET for patients with advanced non-small cell lung cancer |
Date of disclosure of the study information | 2011/11/08 |
Last modified on | 2011/11/07 17:51:02 |
Early prediction of survival to gefitinib or chemotherapy using integrated FDG-PET for patients with advanced non-small cell lung cancer
PET trial
Early prediction of survival to gefitinib or chemotherapy using integrated FDG-PET for patients with advanced non-small cell lung cancer
PET trial
Japan |
non-small cell lung cancer
Pneumology |
Malignancy
NO
to assess the integrated 18-fluorodeoxyglucose positron emission tomography (FDG-PET) at 3 day after treatment as a tool for early response predictor in patients treated with gefitinib or carboplatin plus paclitaxel (CP) prospectively.
Efficacy
FDG-PET was performed before and 3 day after initiation of each treatment. Based on previous studies, a reduction of tumor FDG uptake was assessed by using standardized uptake value (SUV).
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Diagnosis
Device,equipment |
PET examination
Not applicable |
Not applicable |
Male and Female
The main eligibility criterion was pathologically confirmed stage IIIB or IV NSCLC. Additional criteria were as follows: (1) Eastern Cooperative Oncology Group performance status from 0 to 2, (2) bidimensionally measurable lesion(s) on FDG-PET and CT scans, (3) no prior chemotherapy or prior molecular-targeted therapy.
The patients with uncontrolled diabetes mellitus, defined as fasting blood glucose higher than 150 mg/dl, were excluded.
40
1st name | |
Middle name | |
Last name | Minoru Takada |
Kinki University Sakai Hospital
Medical Oncology
2-7-2 Harayamadai, Minami-ku, Sakai, Osaka591-0132, Japan
1st name | |
Middle name | |
Last name | Masaki Kanazu |
Kinki-chuo Chest Medical Center
Internal Medicine
kanamasa@kch.hosp.go.jp
Kinki-chuo Chest Medical Center
Foundation for intractable diseases
Non profit foundation
NO
2011 | Year | 11 | Month | 08 | Day |
Partially published
Completed
2007 | Year | 10 | Month | 12 | Day |
2007 | Year | 10 | Month | 01 | Day |
2011 | Year | 11 | Month | 07 | Day |
2011 | Year | 11 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007896
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