Unique ID issued by UMIN | UMIN000006979 |
---|---|
Receipt number | R000008236 |
Scientific Title | Significance of FFR measurements just after DES implantation for the prediction of prognosis |
Date of disclosure of the study information | 2012/01/01 |
Last modified on | 2023/03/16 18:59:53 |
Significance of FFR measurements just after DES implantation for the prediction of prognosis
The prediction of prognosis just after DES implantation
Significance of FFR measurements just after DES implantation for the prediction of prognosis
The prediction of prognosis just after DES implantation
Japan |
stable angina pectoris, unstable angina pectoris, acute myocardial infarction, old myocardial infarction
Cardiology |
Others
NO
To investigate the significance of FFR measurements just after DES implantation for the prediction of prognosis
Bio-availability
Exploratory
Pragmatic
Not applicable
death, myocardial infarction, cerebrovascular accident, target vessel revascularization
Observational
Not applicable |
Not applicable |
Male and Female
Patients, whose FFR and pull-back intracoronary pressure were measured just after DES implantation
1) Patients, with DES implantation for vessels receiving collateral perfusion
2) Patients treated with 2-stents-stratery for bifurcate lesion
3) Patients, treated for same vessels that have been already implanted DES in
4) Patients, planned PCI for other vessels than DES implanted
5) Patients, post CABG
6) Patients, apparantly having cardiomyopathy
500
1st name | Nobuhiro |
Middle name | |
Last name | Tanaka |
Tokyo Medical University Hospital
Department of Cardiology
1600023
6-7-1Nishishinjuku, Shinjuku-ku, Tokyo, Japan
03-3342-6111
n-tanaka@tokyo-med.ac.jp
1st name | Yohei |
Middle name | |
Last name | Hokama |
Tokyo Medical University Hospital
Department of Cardiology
1600023
6-7-1Nishishinjuku, Shinjuku-ku, Tokyo, Japan
03-3342-6111
y-hokama@tokyo-med.ac.jp
Tokyo Medical University Hospital
Tokyo Medical University Hospital
Self funding
Tokyo Medical University
6-7-1Nishishinjuku, Shinjuku-ku, Tokyo, Japan
03-3342-6111
d-somu@tokyo-med.ac.jp
NO
2012 | Year | 01 | Month | 01 | Day |
none
Published
https://doi.org/10.1016/j.jjcc.2020.12.001
218
During follow up of 31.4months, 34 patients(16%) had cardiovascular events. Inadequate FFR group was significantly associated with higher risk of MACE. In particular, the incidence of unplanned coronary revascularization on non-target lesions was significantly higher in the inadequate FFR group.
2023 | Year | 03 | Month | 16 | Day |
218 patients were included in this study and were divided into two groups.
adequate FFR group (post-stent FFR is greater than 0.80, n=176) vs inadequate FFR group (post-stent FFR is 0.80 or less, n=42).
This study is a prospective multi-institutional research that observed consecutive cases in which FFR was measured after DES implantation during the period from September 2011 to January 2013. Totally, 218 patients were included in this study and were divided into two groups.
Group1:post-stent FFR is greater than 0.80, n=176
Group2:post-stent FFR is 0.80 or less, n=42
none
The primary endpoint was a major adverse cardiovascular event (MACE) including cardiac death, non-fatal myocardial infarction (MI), unplanned coronary revascularization, and hospitalization for heart failure. The secondary endpoints were event rate of all-cause death, non-fatal MI, unplanned coronary revascularization, non-fatal stroke, and hospitalization for heart failure.
Completed
2012 | Year | 01 | Month | 01 | Day |
2012 | Year | 02 | Month | 29 | Day |
2012 | Year | 09 | Month | 01 | Day |
2018 | Year | 01 | Month | 31 | Day |
2023 | Year | 03 | Month | 14 | Day |
2023 | Year | 03 | Month | 14 | Day |
2023 | Year | 03 | Month | 14 | Day |
The results of this study were published in the Journal of Cardiology 77 (2021) 532-538.
2011 | Year | 12 | Month | 28 | Day |
2023 | Year | 03 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000008236
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |