Unique ID issued by UMIN | UMIN000007106 |
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Receipt number | R000008371 |
Scientific Title | Trial of Atheroma Regression Evaluated with Integrated Backscatter Intravascular Ultrasound by administering Sitagliptin |
Date of disclosure of the study information | 2012/02/01 |
Last modified on | 2015/07/25 12:35:02 |
Trial of Atheroma Regression Evaluated with Integrated Backscatter Intravascular Ultrasound by administering Sitagliptin
TRUST Study
Trial of Atheroma Regression Evaluated with Integrated Backscatter Intravascular Ultrasound by administering Sitagliptin
TRUST Study
Japan |
Stable coronary artery disease patients with type 2 diabetes
Cardiology |
Others
NO
Comparison of effect of DPP-4 inhibitor and non-DPP-4 inhibitor on coronary atherosclerosis and plaque composition
Safety,Efficacy
Change in plaque volume using Intravascular Ultrasound (IVUS)
Change in plaque composition using Integrated Backscatter Intravascular Ultrasound (IB-IVUS), and change in lipids and glucose markers, and hs-CRP
Interventional
Parallel
Randomized
Open -but assessor(s) are blinded
Active
2
Treatment
Medicine |
Sitagliptn
Sulfonylurea
20 | years-old | <= |
Not applicable |
Male and Female
1)Patients with type 2 diabetes
2)6.1%<=HbA1c <9.0% (JDS) or 6.5%<=HbA1c <9.4% (NGSP)
3)Stable coronary artery disease
1)Patients with type 1diabetes
2)Patients with ACS
3)patients with contraindication of antiplatelet drug
4)Patients with severe ketosis, diabetic coma or precoma within 6 months
5)Patients with severe infections, before or after operation, or serious trauma .
6)Patients with moderate renal dysfunction (sCr: male>1.5mg/dl, female>1.3mg/dl)
7)Patients who are pregnant, breast-feeding and/or intention to become pregnant
8)Patients with allergy against sitagliptin
9)Other patients determined to be inappropriate by physician
40
1st name | |
Middle name | |
Last name | Ichiro Michishita |
Yokohama Sakae Kyosai Hospital
Division of Cardiology, Department of Internal Medicine
132 Katsura-cho, Sakae-ku, Yokohama
045-891-2171
i-michishita@yokohamasakae.jp
1st name | |
Middle name | |
Last name | Tsuyoshi Nozue |
Yokohama Sakae Kyosai Hospital
Division of Cardiology, Department of Internal Medicine
132 Katsura-cho, Sakae-ku, Yokohama
045-891-2171
nozue2493@yahoo.co.jp
Kanagawa PTCA Conference
Japan Heart Foundation
Non profit foundation
NO
2012 | Year | 02 | Month | 01 | Day |
Unpublished
Completed
2012 | Year | 01 | Month | 19 | Day |
2012 | Year | 02 | Month | 01 | Day |
2015 | Year | 01 | Month | 31 | Day |
2012 | Year | 01 | Month | 20 | Day |
2015 | Year | 07 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000008371
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