Unique ID issued by UMIN | UMIN000009883 |
---|---|
Receipt number | R000009527 |
Scientific Title | Adjustment of blood coagulation for cardiopulmonary bypass surgery: Optimal dosage of tranexamic acid using thromboelastometry |
Date of disclosure of the study information | 2013/01/28 |
Last modified on | 2019/08/29 13:55:41 |
Adjustment of blood coagulation for cardiopulmonary bypass surgery: Optimal dosage of tranexamic acid using thromboelastometry
Optimal dosage of tranexamic acid for cardiopulmonary bypass surgery
Adjustment of blood coagulation for cardiopulmonary bypass surgery: Optimal dosage of tranexamic acid using thromboelastometry
Optimal dosage of tranexamic acid for cardiopulmonary bypass surgery
Japan |
patients undergoig cardiac surgery with cardiopulmonary bypass
Vascular surgery | Anesthesiology |
Others
NO
To investigate dose of tranexamic acid which reduse perioperative blood loss and/or is uneffective for postoperative seizures activity in patients undergoing cardiac surgery with cardiopulmonary bypass
Safety,Efficacy
perioperative blood loss, perioperative fibrinolytic system, ICU stay, postoperative seizure
Interventional
Parallel
Randomized
Double blind -all involved are blinded
Dose comparison
3
Treatment
Medicine |
loding dose of tranexamic acid 12.5mg/kg,contnuous dose 6.5mg/kg/hr, extracorporealcirculation circuit dose 1mg/kg
loding dose of tranexamic acid 21mg/kg,contnuous dose 11mg/kg/hr, extracorporealcirculation circuit dose 1.5mg/kg
loding dose of tranexamic acid 30mg/kg,contnuous dose 16mg/kg/hr, extracorporealcirculation circuit dose 2mg/kg
20 | years-old | <= |
Not applicable |
Male and Female
patients undergoing cardiac surgery using extracorporeal circulation
(a written informed consent was obtained from each participant),first coronary artery bypass grafting/mitral valve plasty/mitral valve replacement/aortic valve replacement
renal dysfunction
90
1st name | |
Middle name | |
Last name | Sungsam Cho |
Nagasaki University Hospital
Anesthesiology
1-7-1,sakamoto,nagasaki city,nagasaki
095-819-7370
chos@nagasaki-u.ac.jp
1st name | |
Middle name | |
Last name | Sungsam Cho |
Nagasaki University Hospital
Anesthesiology
1-7-1,sakamoto,nagasaki city,nagasaki
095-819-7370
chos@nagasaki-u.ac.jp
Nagasaki univesity Hospital
Anaesthesiology
NO
2013 | Year | 01 | Month | 28 | Day |
Unpublished
Completed
2012 | Year | 07 | Month | 01 | Day |
2012 | Year | 06 | Month | 08 | Day |
2012 | Year | 07 | Month | 01 | Day |
2014 | Year | 08 | Month | 01 | Day |
2013 | Year | 01 | Month | 28 | Day |
2019 | Year | 08 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000009527
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |