Unique ID issued by UMIN | UMIN000008234 |
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Receipt number | R000009705 |
Scientific Title | Effect of augmentation therapy with tandospirone on cognition and social function in schizophrenia |
Date of disclosure of the study information | 2012/06/22 |
Last modified on | 2012/06/22 16:37:11 |
Effect of augmentation therapy with tandospirone on cognition and social function in schizophrenia
Cognition and tandospirone augmentation
Effect of augmentation therapy with tandospirone on cognition and social function in schizophrenia
Cognition and tandospirone augmentation
Japan |
schizophrenia
Psychiatry |
Others
NO
To investigate the effect of tandospirone, a serotonin 5-HT1A partial agonist, on cognitive and social function in patients with schizophrenia.
Efficacy
Exploratory
Pragmatic
Not applicable
Schizophrenia Cognition Rating Scale-Japanese version (SCoRS-J)
Brief Assessment of Cognition in Schizophrenia - Japanese version (BACS-J)
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
No treatment
NO
NO
Institution is considered as a block.
YES
Central registration
2
Treatment
Medicine |
60 mg/day tandospirone added
tandospirone not added
20 | years-old | <= |
60 | years-old | >= |
Male and Female
1) meets DSM-IV criteria for schizophrenia or schizoaffective disorder
2) good responder to antipsychotic treatment
3)PANSS score 70 or less
4)had been treated with blonanserine for 2 months or more
5) gave written informed consent
1) Suicide attempt within 6 months before entry
2) Treated with a depot antipsychotic
3) Prescribed anticholinergic drugs and/or tricyclic antidepressants
4)Dependence on alcohol and/or illicit drugs
5) past history of head injury and/or seizure
6) IQ less than 75
7) pregnant
8) BACS and/or UPSA administered within past 3 months
80
1st name | |
Middle name | |
Last name | Tomiki Sumiyoshi |
University of Toyama
Department of Neuropsychiatry
2630 Sugitani, Toyama
076-434-7323
1st name | |
Middle name | |
Last name | Yuko Mizukami |
University of Toyama
Department of Neuropsychiatry
2630 Sugitani, Toyama
076-434-7323
yk1022@med.u-toyama.ac.jp
Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences
Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences
Japan
St Marianna Medical University
Kanazawa Medical University
Osaka University
Kansai Medical University
Jikei Hospital
Okayama University
Hizen Psychiatric Center
N/A
NO
2012 | Year | 06 | Month | 22 | Day |
Unpublished
Preinitiation
2012 | Year | 06 | Month | 14 | Day |
2012 | Year | 07 | Month | 01 | Day |
2013 | Year | 06 | Month | 01 | Day |
2013 | Year | 07 | Month | 01 | Day |
2013 | Year | 08 | Month | 01 | Day |
2013 | Year | 09 | Month | 01 | Day |
2012 | Year | 06 | Month | 22 | Day |
2012 | Year | 06 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000009705
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