UMIN-CTR Clinical Trial
| Unique ID issued by UMIN | UMIN000009168 |
|---|---|
| Receipt number | R000010759 |
| Scientific Title | The functional analysis of immune receptors on human primary mast cell |
| Date of disclosure of the study information | 2012/10/25 |
| Last modified on | 2016/04/22 13:35:44 |
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Basic information
Public title
The functional analysis of immune receptors on human primary mast cell
Acronym
The functional analysis of immune receptors on human primary mast cell
Scientific Title
The functional analysis of immune receptors on human primary mast cell
Scientific Title:Acronym
The functional analysis of immune receptors on human primary mast cell
Region
| Japan |
Condition
Condition
diffuse lung diseases
Classification by specialty
| Pneumology | Adult |
Classification by malignancy
Others
Genomic information
YES
Objectives
Narrative objectives1
To clarify the expression and function of immune receptors on human primary mast cell in airway.
Basic objectives2
Others
Basic objectives -Others
To establish the methodology of cellular biological analysis for human primary mast cell
Trial characteristics_1
Exploratory
Trial characteristics_2
Developmental phase
Not applicable
Assessment
Primary outcomes
expression and function of immune receptors, and identification of novel immune receptors on human primary mast cell.
Key secondary outcomes
Base
Study type
Observational
Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment
Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10
Eligibility
Age-lower limit
| Not applicable |
Age-upper limit
| Not applicable |
Gender
Male and Female
Key inclusion criteria
Broncho alveolar lavage fluid samples obtained from the patient with diffuse lung diseases who had applicablity of broncho alveolar lavage test.
Key exclusion criteria
none
Target sample size
30
Research contact person
Name of lead principal investigator
| 1st name | |
| Middle name | |
| Last name | Akira Shibuya |
Organization
Division of Biomedical sciences, Faculty of Medicine
Division name
Department of immunology
Zip code
Address
1-1-1, Ten-nodai, Tsukuba, Ibaraki, JAPAN
TEL
029-853-3281
ashibuya@md.tsukuba.ac.jp
Public contact
Name of contact person
| 1st name | |
| Middle name | |
| Last name | Kei Nagai |
Organization
University of Tsukuba
Division name
Immunology
Zip code
Address
1-1-1, Ten-nodai, Tsukuba, Ibaraki, JAPAN
TEL
029-853-3281
Homepage URL
s1030509@u.tsukuba.ac.jp
Sponsor or person
Institute
University of Tsukuba
Institute
Department
Personal name
Funding Source
Organization
Create revolutionary technological seeds for science and technology innovation (CREST), Japan science and technology agency (JST)
Organization
Division
Category of Funding Organization
Nationality of Funding Organization
JAPAN
Other related organizations
Co-sponsor
Name of secondary funder(s)
IRB Contact (For public release)
Organization
Address
Tel
Secondary IDs
Secondary IDs
NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW
Institutions
Institutions
筑波大学附属病院(茨城県)
Other administrative information
Date of disclosure of the study information
| 2012 | Year | 10 | Month | 25 | Day |
Related information
URL releasing protocol
Publication of results
Published
Result
URL related to results and publications
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076160
Number of participants that the trial has enrolled
Results
We determined expression and function of immunoreceptors (mainly, Allergin-1) in this study.
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description
Progress
Recruitment status
Completed
Date of protocol fixation
| 2012 | Year | 10 | Month | 20 | Day |
Date of IRB
Anticipated trial start date
| 2012 | Year | 10 | Month | 25 | Day |
Last follow-up date
| 2014 | Year | 12 | Month | 01 | Day |
Date of closure to data entry
| 2015 | Year | 03 | Month | 31 | Day |
Date trial data considered complete
| 2015 | Year | 03 | Month | 31 | Day |
Date analysis concluded
| 2015 | Year | 06 | Month | 01 | Day |
Other
Other related information
To evaluate the expression and function of immune receptors on human primary mast cell in airway with diffuse lung diseases in vitro. To identify a novel immune receptor from gene obtained from isolated human primary mast cell in airway.
Management information
Registered date
| 2012 | Year | 10 | Month | 23 | Day |
Last modified on
| 2016 | Year | 04 | Month | 22 | Day |
Link to view the page
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000010759
| Research Plan | |
|---|---|
| Registered date | File name |
| Research case data specifications | |
|---|---|
| Registered date | File name |
| Research case data | |
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| Registered date | File name |
